Evidence map›Paper›PMID 32661687›Full record

ArticleArchives of toxicology2020

TatS: a novel in vitro tattooed human skin model for improved pigment toxicology research.

Henrik Hering, Christian Zoschke, Markus Kühn, Ashish K Gadicherla, Günther Weindl, Andreas Luch, Ines Schreiver

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Archives of toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
15.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Henrik HeringDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany. Henrik.Hering@bfr.bund.de.ORCID 0000-0003-3951-6736
Christian ZoschkeInstitute of Pharmacy (Pharmacology and Toxicology), Freie Universität Berlin, Berlin, Germany.ORCID 0000-0003-2535-3606
Markus KühnDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
Ashish K GadicherlaDepartment of Biological Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.
Günther WeindlInstitute of Pharmacy (Pharmacology and Toxicology), Freie Universität Berlin, Berlin, Germany.ORCID 0000-0002-4493-7597
Andreas LuchDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany.ORCID 0000-0002-5866-901X
Ines SchreiverDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany. Ines.Schreiver@bfr.bund.de.ORCID 0000-0001-9313-7193
Federal Institute for Risk Assessment · DEFreie Universität Berlin · DEUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reports of tattoo-associated risks boosted the interest in tattoo pigment toxicity over the last decades. Nonetheless, the influence of tattoo pigments on skin homeostasis remains largely unknown. In vitro systems are not available to investigate the interactions between pigments and skin. Here, we established TatS, a reconstructed human full-thickness skin model with tattoo pigments incorporated into the dermis. We mixed the most frequently used tattoo pigments carbon black (0.02 mg/ml) and titanium dioxide (TiO

Indexed as

InkCells, CulturedCell SurvivalCoculture TechniquesColoring AgentsCytokinesDermisFibroblastsFilaggrin ProteinsHumansKeratinocytesSootTattooingTitaniumColoring AgentsCytokinesFilaggrin ProteinsFLG protein, humanSootTitaniumtitanium dioxideAnataseCarbon blackPigment Orange 13RutileTattooingTissue engineering

Identifiers

PMID32661687
PMCPMC7367916
OpenAlexW3043227731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.