Evidence map›Paper›PMID 32661647›Full record

ArticleInfection2020

Emerging echinocandin-resistant Candida albicans and glabrata in Switzerland.

A T Coste, A Kritikos, J Li, N Khanna, D Goldenberger, C Garzoni, C Zehnder, K Boggian, D Neofytos, A Riat and 4 more

Abstract read
In one paragraph

Article in Infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Antimicrobial Resistance ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
  13. Antifungal activity of tannic acid against Candida spp. and its mechanism of action.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Fighting Emerging Caspofungin-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  18. Journal of fungi (Basel, Switzerland) · 2024
    Review
  19. Article
  20. Two promisingFrontiers in pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

A T Coste *Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
A Kritikos *Service of Infectious Diseases, Centre Hospitalier Universitaire Vaudois, Lausanne University Hospital and University of Lausanne, Rue du Bugnon 46, 1011, Lausanne, Switzerland.
J LiInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
N KhannaDivision of Infectious Diseases and Hospital Epidemiology, University and University Hospital of Basel, Basel, Switzerland.
D GoldenbergerDivision of Clinical Bacteriology and Mycology, University and University Hospital of Basel, Basel, Switzerland.
C GarzoniClinica Luganese Moncucco, Lugano, Switzerland.
C ZehnderSYNLAB Suisse SA, Bioggio, Switzerland.
K BoggianDivision of Infectious Diseases and Hospital Epidemiology, Kantonsspital St.Gallen, St.Gallen, Switzerland.
D NeofytosService of Infectious Diseases, Geneva University Hospitals, Geneva, Switzerland.
A RiatService of Laboratory Medicine, Geneva University Hospitals, Geneva, Switzerland.
D BachmannInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
D SanglardInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
F LamothInstitute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. frederic.lamoth@chuv.ch.ORCID http://orcid.org/0000-0002-1023-5597
Fungal Infection Network of Switzerland (FUNGINOS)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Echinocandins represent the first-line therapy of candidemia. Echinocandin resistance among Candida spp. is mainly due to acquired FKS mutations. In this study, we report the emergence of FKS-mutant Candida albicans/glabrata in Switzerland and provide the microbiological and clinical characteristics of 9 candidemic episodes. All patients were previously exposed to echinocandins (median 26 days; range 15-77). Five patients received initial echinocandin therapy with persistent candidemia in 4 of them. Overall mortality was 33%.

Indexed as

Drug Resistance, FungalAdultAgedAged, 80 and overAntifungal AgentsCandida albicansCandida glabrataCandidemiaEchinocandinsFemaleHumansMaleMiddle AgedSwitzerlandAntifungal AgentsEchinocandins

Identifiers

PMID32661647
PMCPMC7518979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.