ArticlePediatric nephrology (Berlin, Germany)2020
Ambulatory hemodynamic patterns, obesity, and pulse wave velocity in children and adolescents.
Article in Pediatric nephrology (Berlin, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Effect of exercise training on arterial stiffness in obese and overweight children: a meta-analysis.European journal of pediatrics · 2022Pooled it
- The relationship between blood pressure variability, left ventricular hypertrophy, and arterial stiffness in children and adolescents with obesity.Pediatric nephrology (Berlin, Germany) · 2026Article
- Precision approaches to paediatric hypertension: linking pathophysiology to therapy.Pediatric nephrology (Berlin, Germany) · 2026Review
- Impact of obesity on arterial health among young adults: A bioelectrical impedance study.Bioinformation · 2026Article
- Systemic Inflammation and Oxidative Stress in Childhood Obesity: Sex Differences in Adiposity Indices and Cardiovascular Risk.Biomedicines · 2024Article
- Cardiorespiratory Fitness Is an Indicator of Arterial Stiffness and Aortic Blood Pressure in Healthy Adolescents.Children (Basel, Switzerland) · 2024Article
- Blood pressure parameters affecting ventricular repolarization in obese children.Pediatric nephrology (Berlin, Germany) · 2023Article
- Adverse childhood experiences are associated with vascular changes in adolescents that are risk factors for future cardiovascular disease.Pediatric nephrology (Berlin, Germany) · 2023Article
- Arterial stiffness and blood pressure increase in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2023Article
- Arterial stiffness indices, pulse wave velocity and central systolic blood pressure, are able to discriminate between obese and non-obese children.European journal of pediatrics · 2023Article
- Ambulatory Blood Pressure Monitoring in Children and Adolescents: 2022 Update: A Scientific Statement From the American Heart Association.Hypertension (Dallas, Tex. : 1979) · 2022Review
- The Role of Urate in Cardiovascular Risk in Adolescents and Young Adults With Hypertension, Assessed by Pulse Wave Velocity.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn recent years, pulse wave velocity (PWV) has emerged as a surrogate marker of cardiovascular disease in children with cardiovascular risk factors. The aims of the present study were to identify determinants of PWV in children according to their weight status and to investigate the role of peripheral blood pressure and central hemodynamic parameters in the association between PWV and obesity.
methodsWe included in the study healthy children and adolescents randomly selected from a school-based blood pressure screening study. All participants underwent ambulatory blood pressure monitoring and 24-h pulse wave analysis.
resultsOverweight and obese children had higher 24-h PWV, 24-h peripheral and central systolic blood pressure (SBP), and cardiac output than normal weight ones. Children with both overweight and hypertension presented the highest 24-h PWV values (p < 0.001). Peripheral and central SBP, body mass index (BMI), and hemodynamic parameters, including stroke volume, cardiac output, total peripheral resistance, and cardiac index, were all associated with 24-h PWV. However, in stepwise regression analysis, 24-h peripheral and central SBP and cardiac index, but not BMI, were independent predictors of 24-h PWV. There were statistically significant differences in 24-h blood pressure and hemodynamic parameters among those on the lower and highest 24-h PWV quartile, but there were no significant differences in BMI among 24-h PWV quartile groups.
conclusionsArterial stiffness is higher in overweight and obese children in the co-presence of hypertension. Peripheral and central SBP are the main determinants of 24-h PWV independent of weight status. Graphical abstract.
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