ArticleAging medicine (Milton (N.S.W))2020
Longer incubation period of coronavirus disease 2019 (COVID-19) in older adults.
Article in Aging medicine (Milton (N.S.W)), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Assessing changes in incubation period, serial interval, and generation time of SARS-CoV-2 variants of concern: a systematic review and meta-analysis.BMC medicine · 2023Pooled it
- Incubation Period of COVID-19 Caused by Unique SARS-CoV-2 Strains: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- The incubation period of COVID-19: a global meta-analysis of 53 studies and a Chinese observation study of 11 545 patients.Infectious diseases of poverty · 2021Pooled it
- Dynamics of infectious disease spread between transportation hubs and surrounding communities.Infectious Disease Modelling · 2026Article
- Defining the Critical Requisites for Accurate Simulation of SARS-CoV-2 Viral Dynamics: Patient Characteristics and Data Collection Protocol.Journal of medical virology · 2025Article
- Latent and incubation periods of Delta, BA.1, and BA.2 variant cases and associated factors: a cross-sectional study in China.BMC infectious diseases · 2024Article
- Evaluation of the EsteR Toolkit for COVID-19 Decision Support: Sensitivity Analysis and Usability Study.JMIR formative research · 2023Article
- Article
- COVID-19 in one region of New Zealand: a descriptive epidemiological study.Australian and New Zealand journal of public health · 2022Article
- COVID-19: the case for aerosol transmission.Interface focus · 2022Review
- Temperature, humidity and outdoor air quality indicators influence COVID-19 spread rate and mortality in major cities of Saudi Arabia.Environmental research · 2022Article
- Effects of prolonged incubation period and centralized quarantine on the COVID-19 outbreak in Shijiazhuang, China: a modeling study.BMC medicine · 2021Article
- Epidemiological characteristics and incubation period of SARS-CoV-2 during the 2020-2021 winter pandemic wave in North China: An observational study.Journal of medical virology · 2021Observational
- Wastewater-Based Epidemiology for Community Monitoring of SARS-CoV-2: Progress and Challenges.ACS environmental Au · 2021Review
- Optimizing testing regimes for the detection of COVID-19 in children and older adults.Expert review of molecular diagnostics · 2021Review
- Modeling the effect of age on quantiles of the incubation period distribution of COVID-19.BMC public health · 2021Article
- COVID-19 patient with an incubation period of 27 d: A case report.World journal of clinical cases · 2021Article
- An intra-host SARS-CoV-2 dynamics model to assess testing and quarantine strategies for incoming travelers, contact management, and de-isolation.Patterns (New York, N.Y.) · 2021Article
- Article
- In pursuit of the right tail for the COVID-19 incubation period.Public health · 2021Review
Corrections and comments
- Erratum issuedCORRIGENDUM.2020
Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to explore any age-related change in the incubation period of COVID-19, specifically any difference between older (aged ≥65 years) and younger adults.
methodsBased on online data released officially by 21 Chinese cities from January 22 to February 15, 2020, the incubation period of COVID-19 patients who had travelled to Hubei was studied according to age. Previous studies were reviewed and compared.
resultsThe study recruited 136 COVID-19 patients who had travelled to Hubei during January 5-31, 2020, stayed for 1-2 days, and returned with symptom onset during January 10-February 6, 2020. The median age was 50.5 years (range 1-86 years), and 22 patients (16.2%) were aged ≥65 years. The age-stratified incubation period was U-shaped with higher values at extremes of age. The median COVID-19 incubation period was 8.3 (90% confidence interval [CI], 7.4-9.2) days for all patients, 7.6 (90% CI, 6.7-8.6) days for younger adults, and 11.2 (90% CI, 9.0-13.5) days for older adults. The 5th/25th/75th/90th percentiles were 2.3/5.3/11.3/14.2 days for all, 2.0/5.0/10.5/13.2 days for younger adults, and 3.1/7.8/14.4/17.0 days for older adults. There were 11 published studies on COVID-19 incubation periods up to March 30, 2020, reporting means of 1.8-7.2 days, and medians of 4-7.5 days, but there was no specific study on the effect of age on incubation period. One study showed that severe COVID-19 cases, which included more elderly patients, had longer incubation periods.
conclusionBased on 136 patients with a travel history to Hubei, the epicenter of COVID-19, the COVID-19 incubation period was found to be longer in older adults. This finding has important implications for diagnosis, prevention, and control of COVID-19.
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