Evidence map›Paper›PMID 32661475›Full record

ArticleInternational journal of clinical and experimental pathology2020

Effects of bone marrow mesenchymal stem cells transplantation on organoretinal culture after hypoxia injury.

Hai Li, Xiao-Ping Zhu, Wen-Zhi Ren, Fu-Shi Quan

Abstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hai LiDepartment of Laboratory Animals, College of Animal Sciences, Jilin University Changchun, Jilin, China.
Xiao-Ping ZhuDepartment of Laboratory Animals, College of Animal Sciences, Jilin University Changchun, Jilin, China.
Wen-Zhi RenDepartment of Laboratory Animals, College of Animal Sciences, Jilin University Changchun, Jilin, China.
Fu-Shi QuanDepartment of Laboratory Animals, College of Animal Sciences, Jilin University Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effects of bone marrow mesenchymal stem cells transplantation on organoretinal cultures after a hypoxia injury.

methodThe retinal tissues were cultured in vitro and then transplanted with bone marrow mesenchymal stem cells. Then, H&E staining and immunohistochemical assay were conducted to investigate the changes in retinal tissue structure and the migration and differentiation of stem cells.

resultsThe retinal tissues were slightly damaged in the stem cell transplantation group; the control group, the retinal tissue structure was changed, and the thinning of their thickness was clearly evident. The transplanted stem cells can migrate to each layer of the retina to replace the damaged dead cells, which can protect the peripheral injured tissues and cells.

Indexed as

migrationorgan culturereplacementRetinastem cell transplantation

Identifiers

PMID32661475
PMCPMC7344008

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.