Evidence map›Paper›PMID 32661394›Full record

ArticleNature neuroscience2020

Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice.

Julie Ouellette, Xavier Toussay, Cesar H Comin, Luciano da F Costa, Mirabelle Ho, María Lacalle-Aurioles, Moises Freitas-Andrade, Qing Yan Liu, Sonia Leclerc, Youlian Pan and 15 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 114 citations in OpenAlex.

  1. Review
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  9. Navigating Central Oxytocin Transport: Known Realms and Uncharted Territories.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025
    Review
  10. Article
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  14. Review
  15. Article
  16. Development of perivascular astrocyte processes.Frontiers in neuroscience · 2025
    Review
  17. Article
  18. Article
  19. Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 8 institutions in 3 countries.

Julie Ouellette *Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Xavier Toussay *Neuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Cesar H CominDepartment of Computer Science, Federal University of São Carlos, São Carlos, Brazil.
Luciano da F CostaSão Carlos Institute of Physics, FCM-USP, University of São Paulo, São Paulo, Brazil.
Mirabelle HoRegenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
María Lacalle-AuriolesMontreal Neurological Institute, McGill University, Montréal, Québec, Canada.
Moises Freitas-AndradeNeuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-5649-9053
Qing Yan LiuNational Research Council of Canada, Human Health and Therapeutics, Ottawa, Ontario, Canada.
Sonia LeclercNational Research Council of Canada, Human Health and Therapeutics, Ottawa, Ontario, Canada.
Youlian PanDigital Technologies, National Research Council of Canada, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-0158-0081
Ziying LiuDigital Technologies, National Research Council of Canada, Ottawa, Ontario, Canada.
Jean-François ThibodeauKidney Research Center, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-9322-4868
Melissa YinFUJIFILM VisualSonics, Toronto, Ontario, Canada.
Micael CarrierAxe Neurosciences, Centre de recherche du CHU de Québec, Université Laval, Québec, Québec, Canada.ORCID http://orcid.org/0000-0002-0658-2828
Cameron J MorseNeuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Peter Van DykenNeuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Christopher J BerginDepartment of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Sylvain BailletMontreal Neurological Institute, McGill University, Montréal, Québec, Canada.ORCID http://orcid.org/0000-0002-6762-5713
Christopher R KennedyKidney Research Center, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Marie-Ève TremblayAxe Neurosciences, Centre de recherche du CHU de Québec, Université Laval, Québec, Québec, Canada.ORCID http://orcid.org/0000-0003-2863-9626
Yannick D BenoitDepartment of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
William L StanfordRegenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Dylan BurgerKidney Research Center, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Duncan J StewartRegenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-9113-8691
Baptiste LacosteNeuroscience Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. blacoste@uottawa.ca.ORCID http://orcid.org/0000-0002-1922-8801
University of Ottawa · CAOttawa Hospital · CANational Research Council Canada · CACentre hospitalier de l'Université Laval · CAMontreal Neurological Institute and Hospital · CAFujiFilm VisualSonics (Canada) · CAUniversidade de São Paulo · BRUniversidade Federal de São Carlos · BR

Funding

CIHR 388805
6 · The paper itself

Abstract

While the neuronal underpinnings of autism spectrum disorder (ASD) are being unraveled, vascular contributions to ASD remain elusive. Here, we investigated postnatal cerebrovascular development in the 16p11.2

Indexed as

AnimalsAutism Spectrum DisorderAutistic DisorderCerebrovascular CirculationChromosome DeletionChromosome DisordersChromosomes, Human, Pair 16Disease Models, AnimalEndothelial CellsFemaleIntellectual DisabilityMaleMiceNeovascularization, PhysiologicNeurovascular Coupling

Identifiers

PMID32661394
OpenAlexW3041925125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.