ArticleJournal of biosciences2020
Choline-betaine pathway contributes to hyperosmotic stress and subsequent lethal stress resistance in
Article in Journal of biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Effects of sublethal stress application on the survival of bacterial inoculants: a systematic review.Archives of microbiology · 2023Pooled it
- RNA-Seq Insight into the Impact and Mechanisms of Methyl Donor and Glycine Betaine Osmoprotectant on Polyketide Secondary Metabolism inJournal of fungi (Basel, Switzerland) · 2025Article
- Comparative genomic analysis of two putative novel Idiomarina species from hypersaline miocene deposits.BMC genomics · 2024Article
- Integrated Genomics and Transcriptomics Provide Insights into Salt Stress Response inMicroorganisms · 2024Article
- Exogenous Regulators Enhance the Yield and Stress Resistance of Chlamydospores of the Biocontrol AgentJournal of fungi (Basel, Switzerland) · 2022Article
- Characterizing microbiota and metabolomics analysis to identify candidate biomarkers in lung cancer.Frontiers in oncology · 2022Article
- Quorum Sensing Controls the CRISPR and Type VI Secretion Systems inFrontiers in veterinary science · 2022Article
- Metagenomic Insight into the Community Structure of Maize-Rhizosphere Bacteria as Predicted by Different Environmental Factors and Their Functioning within Plant Proximity.Microorganisms · 2021Article
- Transcriptomic Analysis ofFoods (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pseudomonas protegens SN15-2, a typical non-spore-forming rhizosphere bacterium, has excellent biocontrol capabilities; thus, it is necessary to explore the stress resistance of SN15-2. The choline-glycine betaine pathway is considered as an important mechanism by which bacteria adapt to stressful environments. In this work, we demonstrated that the expression of the betA and betB genes, which are involved in the choline- glycine betaine pathway in SN15-2, was highly increased by 12-fold and 26-fold, respectively, by hyperosmotic stress and choline treatment. The accumulation of betaine in SN15-2 (5.54 g/L) was significantly higher than that in the mutants Δ betA (3.44 g/L) and Δ betB (2.68 g/L) under hyperosmotic stress and choline treatment. Moreover, choline enhanced the growth of SN15-2 greatly, but it did not enhance the growth of Δ betB under hyperosmotic stress. Choline combined with hyperosmotic adaptation significantly increased the lethal stress resistance of SN15-2 while the resistance of Δ betA and Δ betB was significantly decreased. This research illuminated a strategy underlying the adaptation to osmotic stress in
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32661212W3037979894What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.