Evidence map›Paper›PMID 32661163›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Azadeh Aryan, Michelle A E Anderson, James K Biedler, Yumin Qi, Justin M Overcash, Anastasia N Naumenko, Maria V Sharakhova, Chunhong Mao, Zach N Adelman, Zhijian Tu

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 86 citations in OpenAlex.

  1. Article
  2. Rapid turnover of sex-determining architecture in invasive mussels.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Mosquito sex determination: recent advances and applications.Current opinion in insect science · 2025
    Review
  8. Article
  9. Article
  10. Differential elimination of marked sex chromosomes enables production of nontransgenic male mosquitoes in a single strain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Azadeh AryanDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061.ORCID 0000-0001-6469-8573
Michelle A E AndersonDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061.ORCID 0000-0003-1510-2942
James K BiedlerDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061.
Yumin QiDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061.
Justin M OvercashDepartment of Entomology, Texas A&M University, College Station, TX 77843.
Anastasia N NaumenkoFralin Life Science Institute, Virginia Tech, Blacksburg, VA 24061.
Maria V SharakhovaFralin Life Science Institute, Virginia Tech, Blacksburg, VA 24061.ORCID 0000-0002-5790-3548
Chunhong MaoBiocomplexity Institute & Initiative, University of Virginia, Charlottesville, VA 22911.
Zach N AdelmanDepartment of Entomology, Texas A&M University, College Station, TX 77843.ORCID 0000-0001-5901-7171
Zhijian TuDepartment of Biochemistry, Virginia Tech, Blacksburg, VA 24061; jaketu@vt.edu.ORCID 0000-0003-4227-3819
Virginia Tech · USTexas A&M University · USBiocom · USNational Research Tomsk State University · RU

Funding

Mechanism and application of male determination in aedine mosquitoesR01AI123338 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI TU, ZHIJIAN JAKE · 2016 to 2020
$2.9M
Improving the reference genome assembly for the dengue fever vector Aedes aegyptiR21AI121853 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SHARAKHOVA, MARIA · 2016 to 2017
$423k
NIAID NIH HHS R01 AI123338NIAID NIH HHS R21 AI121853
6 · The paper itself

Abstract

A dominant male-determining locus (M-locus) establishes the male sex (M/m) in the yellow fever mosquito,

Indexed as

Flight, AnimalGenes, InsectGenetic Association StudiesAedesAnimalsAnimals, Genetically ModifiedCRISPR-Cas SystemsFemaleGenetic LociGenotypeInheritance PatternsMaleMembrane ProteinsPenetrancePhenotypePromoter Regions, GeneticMembrane ProteinsAedes aegyptiinfectious diseasesM factormosquitosex-determination

Identifiers

PMID32661163
PMCPMC7395513
OpenAlexW3043458365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.