Evidence map›Paper›PMID 32661116›Full record

ArticleJournal for immunotherapy of cancer2020

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of multiple myeloma.

Nina Shah, Jack Aiello, David E Avigan, Jesus G Berdeja, Ivan M Borrello, Ajai Chari, Adam D Cohen, Karthik Ganapathi, Lissa Gray, Damian Green and 9 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in Journal for immunotherapy of cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  4. Frontiers in medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 15 institutions in 1 country.

Nina ShahDivision of Hematology-Oncology, Department of Medicine, University of California San Francisco, San Francisco, California, USA.
Jack AielloPatient Empowerment Network, San Jose, California, USA.
David E AviganDivision of Hematology and Hematologic Malignancies, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Jesus G BerdejaDepartment of Medicine, Sarah Cannon Research Institute, Nashville, Tennessee, USA.
Ivan M BorrelloDepartment of Oncology, The Sidney Kimmel Comprehensive Cancer Center of Johns Hopkins, Baltimore, Maryland, USA.
Ajai ChariHematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Adam D CohenDepartment of Medicine, Abramson Cancer Center at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Karthik GanapathiDepartment of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA.
Lissa GrayUniversity of California San Francisco, San Francisco, CA, USA.
Damian GreenClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Amrita KrishnanDepartment of Hematology and Hematopoietic Cell Transplantation, Judy and Bernard Briskin Multiple Myeloma Center for Clinical Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
Yi LinDivision of Hematology, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Elisabet ManasanchDepartment of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Nikhil C MunshiJerome Lipper Multiple Myeloma Disease Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
Ajay K NookaDepartment of Hematology/Oncology, Emory University, Atlanta, Georgia, USA.
Aaron P RapoportUniversity of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland, USA.
Eric L SmithMyeloma Service and Cellular Therapeutics Center, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Ravi VijDivision of Medical Oncology, Siteman Cancer Center, Washington University in Saint Louis School of Medicine, Saint Louis, Missouri, USA.
Madhav DhodapkarSchool of Medicine, Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia, USA madhav.v.dhodapkar@emory.edu.
University of California, San Francisco · USEmory University · USBeth Israel Deaconess Medical Center · USCity of Hope · USDana-Farber Cancer Institute · USEmpowerment Program · USFred Hutch Cancer Center · USIcahn School of Medicine at Mount Sinai · USMayo Clinic · USMemorial Sloan Kettering Cancer Center · USSarah Cannon · USSidney Kimmel Comprehensive Cancer Center · USThe University of Texas MD Anderson Cancer Center · USUniversity of Maryland, Baltimore · USUniversity of Pennsylvania · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Outcomes in multiple myeloma (MM) have improved dramatically in the last two decades with the advent of novel therapies including immunomodulatory agents (IMiDs), proteasome inhibitors and monoclonal antibodies. In recent years, immunotherapy for the treatment of MM has advanced rapidly, with the approval of new targeted agents and monoclonal antibodies directed against myeloma cell-surface antigens, as well as maturing data from late stage trials of chimeric antigen receptor CAR T cells. Therapies that engage the immune system to treat myeloma offer significant clinical benefits with durable responses and manageable toxicity profiles, however, the appropriate use of these immunotherapy agents can present unique challenges for practicing physicians. Therefore, the Society for Immunotherapy of Cancer convened an expert panel, which met to consider the current role of approved and emerging immunotherapy agents in MM and provide guidance to the oncology community by developing consensus recommendations. As immunotherapy evolves as a therapeutic option for the treatment of MM, these guidelines will be updated.

Indexed as

ImmunotherapyMultiple MyelomaHumansantineoplastic protocolsguidelines as topichematological neoplasmsimmunotherapyreceptors, chimeric antigen

Identifiers

PMID32661116
PMCPMC7359060
OpenAlexW3041796883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.