Trial reportEuropean journal of hospital pharmacy : science and practice2021
Impact of pharmacist interventions on drug-related problems in general surgery patients: a randomised controlled trial.
Trial report in European journal of hospital pharmacy : science and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- The role of pharmacists in mitigating medication errors in the perioperative setting: a systematic review.Systematic reviews · 2025Pooled it
- Medication review in hospitalised patients to reduce morbidity and mortality.The Cochrane database of systematic reviews · 2023Pooled it
- Pharmacist-led medication reconciliation upon discharge from the orthopedic surgery department.Scientific reports · 2026Trial
- The impact of clinical pharmacist-physician communication on reducing drug-related problems: a mixed study design in a tertiary teaching Hospital in Xinjiang, China.BMC health services research · 2022Trial
- Drug-related problems identified in patients attending primary healthcare centers in Jordan.Medicine · 2026Observational
- Knowledge, attitudes, and behaviors of pharmacy students towards clinical pharmacy in Türkiye: insights from a multicenter cross-sectional study.BMC medical education · 2026Article
- Established and emerging roles for pharmacy in operating theatres: a scoping review.International journal of clinical pharmacy · 2025Article
- Medication use and potential drug-drug interactions in a general surgery clinic: A descriptive study.Heliyon · 2025Article
- Drug therapy problems and associated factors among adult patients admitted to the surgical ward in a resource-limited setting.Frontiers in pharmacology · 2025Article
- Effectiveness of Quality Use of Medicines (QUM) Programs and Strategies in Saudi Arabia: A Narrative Review.Drug, healthcare and patient safety · 2025Review
- Article
- Pharmacist-led interventions for vascular surgery patients: a prospective study on reducing drug-related problems.BMC health services research · 2024Observational
- Development of an innovative clinical pharmacy service in a urology surgical unit: a new initiative from Qatar.Journal of pharmaceutical policy and practice · 2024Article
- Drug Therapy Problems Identified by Clinical Pharmacists at a General Surgery Ward of an Academic Referral Hospital in Jordan.Therapeutics and clinical risk management · 2024Article
- The COVID-19 Pandemic and Patient Safety Culture: A Cross-Sectional Study among Community Pharmacies in Jordan.Healthcare (Basel, Switzerland) · 2022Article
- Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe inappropriate use of medications is harmful and is a common issue in hospitalised patients. Patients hospitalised in general surgery wards are usually at high risk for drug-related problems (DRPs). This randomised controlled trial aimed to explore the value of a pharmaceutical care service conducted in general surgery wards in the identification and reduction of DRPs in comparison with standard medical care.
methodsThis study was conducted in general surgery wards including abdominal, cardiovascular, vascular, endocrine, orthopaedic and oncological surgeries at one of the largest teaching hospitals in Jordan over a period of 6 months. Recruited patients were randomised into intervention or control groups. Clinical pharmacists assessed patients' DRPs and submitted recommendations to resolve the identified DRPs in the intervention group.
resultsPatients in the intervention group (n=63) and the control group (n=60) had a mean age of 55±14.4 years, with 52.0% being women. A total of 1062 DRPs were identified, with a mean of 8.6±3.6 per patient (intervention group, 8.65±4.2; control group, 8.62±2.6; p=0.56). The commonly identified DRPs included safety (20.2%) and efficacy (19.0%) issues. The acceptance rate for pharmacists' recommendations by physicians was very high (90%) with a good DRP correction rate of 58.9% during patients' hospital stay. The value of pharmaceutical care was significantly reflected in the achievement of the therapeutic outcomes and prevention of morbidity (resolved/improved or prevented) of 68.2% (24.2%+44%) in the intervention group compared with 19.2% (12.4%+6.8%) in the control group (p<0.001).
conclusionsThis study shows that DRPs are common among general surgery patients in Jordan, especially those related to drug safety and efficacy. Pharmacists' recommendations contributed substantially to resolving most of the identified DRPs and had a significant impact on improving medications used in general surgery patients.
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