Evidence map›Paper›PMID 32661090›Full record

ArticleJournal of cell science2020

CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly.

Koichiro Otake, Jun-Ichirou Ohzeki, Nobuaki Shono, Kazuto Kugou, Koei Okazaki, Takahiro Nagase, Hisashi Yamakawa, Natalay Kouprina, Vladimir Larionov, Hiroshi Kimura and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of cell science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Sustainable integrative cell biology: CENP-C is guilty by association.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Article
  4. Article
  5. The dynamic centromere.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  6. Article
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  9. Review
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  11. Article
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  14. Review
  15. Centromere drive: model systems and experimental progress.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Koichiro OtakeLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.ORCID 0000-0002-4021-2572
Jun-Ichirou OhzekiLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.
Nobuaki ShonoLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.
Kazuto KugouLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.
Koei OkazakiLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.
Takahiro NagasePublic Relations and Research Promotion Group, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.
Hisashi YamakawaClinical Analysis Team, Department of Omics Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan.
Natalay KouprinaGenome Structure and Function Group, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Vladimir LarionovGenome Structure and Function Group, Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Hiroshi KimuraCell Biology Unit, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan.ORCID 0000-0003-0854-083X
William C EarnshawWellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK.
Hiroshi MasumotoLaboratory of Chromosome Engineering, Department of Frontier Research and Development, Kazusa DNA Research Institute, 2-6-7 Kazusa-Kamatari, Kisarazu 292-0818, Japan masumoto@kazusa.or.jp.ORCID 0000-0001-6960-4417
Kazusa DNA Research Institute · JPNational Institutes of Health · USTokyo Institute of Technology · JPWellcome Centre for Cell Biology · GB

Funding

Study of hereditary prostate cancer and human artificial chromosomesZIABC010413 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LARIONOV, VLADIMIR · 2009 to 2025
$31.5M
Wellcome TrustWellcome Trust 073915
6 · The paper itself

Abstract

CENP-B binds to CENP-B boxes on centromeric satellite DNAs (known as alphoid DNA in humans). CENP-B maintains kinetochore function through interactions with CENP-A nucleosomes and CENP-C. CENP-B binding to transfected alphoid DNA can induce

Indexed as

ChromatinHeterochromatinAutoantigensCentromereCentromere Protein AChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneEpigenesis, GeneticHumansAutoantigensCBX1 protein, humanCBX3 protein, humanCBX5 protein, humanCentromere Protein AChromatinChromobox Protein Homolog 5Chromosomal Proteins, Non-HistoneHeterochromatinAcidic-rich domainAlternative epigenetic statesASH1LCENP-BCentromereHP1

Identifiers

PMID32661090
PMCPMC7438015
OpenAlexW3041553421

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.