Evidence map›Paper›PMID 32660986›Full record

ArticleAntimicrobial agents and chemotherapy2020

Pharmacodynamic Evaluation of Plasma and Epithelial Lining Fluid Exposures of Amikacin against Pseudomonas aeruginosa in a Dynamic

Aaron J Heffernan, Fekade B Sime, Derek S Sarovich, Michael Neely, Yarmarly Guerra-Valero, Saiyuri Naicker, Kyra Cottrell, Patrick Harris, Katherine T Andrews, David Ellwood and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Aaron J HeffernanSchool of Medicine, Griffith University, Gold Coast, Queensland, Australia aaron.heffernan@griffithuni.edu.au.ORCID 0000-0002-7929-9812
Fekade B SimeCentre for Translational Anti-Infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0003-4061-2063
Derek S SarovichGeneCology Research Centre, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.
Michael NeelyChildren's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California, USA.
Yarmarly Guerra-ValeroUniversity of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Saiyuri NaickerCentre for Translational Anti-Infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia.
Kyra CottrellUniversity of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Patrick HarrisUniversity of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0002-2895-0345
Katherine T AndrewsGriffith Institute for Drug Discovery, Griffith University, Nathan, Queensland, Australia.
David EllwoodSchool of Medicine, Griffith University, Gold Coast, Queensland, Australia.
Steven C WallisUniversity of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Jeffrey LipmanUniversity of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Keith GrimwoodSchool of Medicine, Griffith University, Gold Coast, Queensland, Australia.
Jason A RobertsCentre for Translational Anti-Infective Pharmacodynamics, School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0001-6218-435X
The University of Queensland · AUGriffith University · AUUniversity of Southern California · USUniversity of the Sunshine Coast · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given that aminoglycosides, such as amikacin, may be used for multidrug-resistant

Indexed as

AmikacinPseudomonas InfectionsAminoglycosidesAnti-Bacterial AgentsHumansMicrobial Sensitivity TestsPseudomonas aeruginosaAmikacinAminoglycosidesAnti-Bacterial AgentsamikacinpharmacodynamicsPseudomonas aeruginosaventilator-associated pneumonia

Identifiers

PMID32660986
PMCPMC7449155
OpenAlexW3041051570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.