ArticleKnee surgery & related research2020
Hypoalbuminemia and obesity class II are reliable predictors of peri-prosthetic joint infection in patient undergoing elective total knee arthroplasty.
Article in Knee surgery & related research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Associations between preoperative hypoalbuminemia and clinical outcomes following total hip or knee arthroplasty: a systematic review and meta-analysis.EFORT open reviews · 2026Pooled it
- Incidence of periprosthetic joint infection after primary total knee arthroplasty shows significant variation : a synthesis of meta-analysis and bibliometric analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- Effect of serologic malnutrition on postoperative wound infection problems after total joint arthroplasty: A meta-analysis.International wound journal · 2023Pooled it
- Nutritional disorders have adverse effect on clinical outcomes and may increase healthcare costs following hip and knee arthroplasty-A systematic review.Journal of experimental orthopaedics · 2026Review
- The Geriatric Nutritional Risk Index Is an Independent Predictor of Prosthesis Aseptic Loosening in Patients Undergoing Total Joint Arthroplasty.Orthopaedic surgery · 2026Article
- C-Reactive Protein to Albumin Ratio and Prognostic Nutrition Index as a Predictor of Periprosthetic Joint Infection and Early Postoperative Wound Complications in Patients Undergoing Primary Total Hip and Knee Arthroplasty.Diagnostics (Basel, Switzerland) · 2025Article
- Evaluation of the Diagnostic Accuracy of Serum Albumin and Globulin in Pyogenic Spondylitis.Journal of clinical medicine · 2025Article
- Enhanced Diagnostic Accuracy for Septic Arthritis Through Multivariate Analysis of Serum and Synovial Biomarkers.Journal of clinical medicine · 2025Article
- The dynamics of perioperative serum albumin before and after total knee arthroplasty.Journal of orthopaedics · 2024Article
- Postoperative decrease in serum albumin as predictor of early acute periprosthetic infection after total knee arthroplasty.Journal of orthopaedic surgery and research · 2024Article
- Improved outcomes with perioperative dietitian-led interventions in patients undergoing total joint arthroplasty: A systematic review.Journal of orthopaedics · 2024Review
- Association between disease activity of rheumatoid arthritis and risk of complications following total hip arthroplasty: a retrospective cohort study.Journal of orthopaedic surgery and research · 2024Article
- Prevalence of Poor Nutrition in Knee Osteoarthritis Patients: A Hospital-Based Cohort Study in Indian Population.Indian journal of orthopaedics · 2024Article
- Accuracy of Albumin, Globulin, and Albumin-Globulin Ratio for Diagnosing Periprosthetic Joint Infection: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Single use Negative Pressure Wound Therapy (NPWT) system in the management of knee arthroplasty.BMC musculoskeletal disorders · 2023Article
- Hypoalbuminemia Increases Mortality after Two-Stage Revision Total Joint Arthroplasty.The archives of bone and joint surgery · 2023Article
- Information and BMI limits for patients with obesity eligible for knee arthroplasty: the Swedish surgeons' perspective from a nationwide cross-sectional study.Journal of orthopaedic surgery and research · 2022Article
- Risk Factors for Periprosthetic Joint Infection after Primary Total Knee Arthroplasty.Journal of clinical medicine · 2022Review
- Traditional Chinese-Hong Kong version of Forgotten Joint Score-12 (FJS-12) for patients with osteoarthritis of the knee underwent joint replacement surgery: cross-cultural and sub-cultural adaptation, and validation.BMC musculoskeletal disorders · 2022Article
- Inflammation and nutrition based screening tests for detection of infection in cases of rapid hip destruction.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMalnutrition is a common and modifiable risk factor for postoperative complications and adverse outcomes in orthopedics. The purpose of this study was to identify biomarkers of malnutrition in patients undergoing elective total knee arthroplasty (TKA) that are predictive of adverse in-hospital postoperative complications, to facilitate the identification of at-risk patients for nutritional optimization before surgery.
methodsA total of 624 patients who underwent elective TKA between 2013 and 2017 were evaluated; potential biomarkers of preoperative malnutrition, including hypoalbuminemia (serum albumin < 3.5 g/dL), total lymphocyte count (TLC < 1500 cells/mm
resultsThe prevalence of hypoalbuminemia, low TLC, overweight, obesity class I, and obesity class II were, respectively 2.72%, 33.4%, 14.8%, 44.5%, and 26.9%. There was a significant association between hypoalbuminemia and obesity class II (BMI ≥ 30.0 kg/m
conclusionsHypoalbuminemia and obesity class II together is a reliable biomarker of preoperative malnutrition for predicting peri-prosthetic joint infection after elective TKA, whereas low TLC, overweight, and obesity class I were not significantly associated with an increased risk of such complications.
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