Trial reportJournal of neuroengineering and rehabilitation2020
Effects of interactive video-game-based exercise on balance in older adults with mild-to-moderate Parkinson's disease.
Trial report in Journal of neuroengineering and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 36 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Interactive Video Game-based Exercise on Balance of Persons With Parkinson's Disease
Effects of Wii Fit Based Exercises and Proprioceptive Training on Balance and Fall Risk in Patients With Diabetic Neuropathy
Effects of Visual Biofeedback Therapy on Balance, Freezing of Gait and Cognition Among Stage III Parkinson's Patients: A Randomized Controlled Trial
Who cites it
36 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Can virtual reality interventions reduce falls in Parkinson's disease? A systematic review and meta-analysis of randomized trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Pooled it
- The Effects of Digital Health Interventions on Motor Symptoms, Nonmotor Symptoms, and Quality of Life in Patients With Parkinson Disease: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Exergaming Compared to Conventional Physical Exercise Interventions on Health Status in Older People with Parkinson's Disease: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Effectiveness of technological interventions on psychosocial well-being and perception of technological interventions among people with Parkinson's disease: A systematic review.Australasian journal on ageing · 2025Pooled it
- Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.The Cochrane database of systematic reviews · 2024Pooled it
- Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.The Cochrane database of systematic reviews · 2023Pooled it
- Pooled it
- Interventions for preventing falls in Parkinson's disease.The Cochrane database of systematic reviews · 2022Pooled it
- The effect of exercise on balance in patients with stroke, Parkinson, and multiple sclerosis: a systematic review and meta-analysis of clinical trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Pooled it
- The size and behavior of virtual objects have influence on functional exercise and motivation of persons with multiple sclerosis: a randomized study.Scientific reports · 2022Trial
- Gamified clinical case video game in occupational therapy.BMC medical education · 2026Article
- Quantifying Slowness in Parkinson Disease Using a Serious Game: Cross-Sectional Study.JMIR serious games · 2026Article
- Technology-Assisted Physical Activity Interventions for Older People in Their Home-Based Environment: Scoping Review.JMIR aging · 2025Article
- Effects of Exercise on Balance, Gait Speed, Quality of Life, and Symptom Relief Among Older Adults with Parkinson's Disease: A Meta-Analysis of Randomized Controlled Trials (RCTs).Healthcare (Basel, Switzerland) · 2025Review
- Gamification Integration in Technological Devices for Motor Rehabilitation in Parkinson Disease: Scoping Review.JMIR serious games · 2025Review
- Biomechanical analysis of patients with mild Parkinson's disease during indoor cycling training.Journal of neuroengineering and rehabilitation · 2025Article
- Virtual reality motor sensing exercise in patients with Parkinson's disease: a scoping review.Frontiers in rehabilitation sciences · 2025Review
- Precision intervention of virtual reality training for balance and gait in Parkinson's disease: a dose-response meta-analysis.Frontiers in neurology · 2025Review
- Neuromotor adaptations in people with Parkinson's Disease following a 12-month multimodal non-contact boxing intervention.Frontiers in human neuroscience · 2025Article
- Effectiveness of Technological Interventions for Older Adults With Parkinson Disease: Systematic Review.JMIR serious games · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to evaluate the effectiveness of a customized interactive video game-based (IVGB) training on balance in older adults with mild-to-moderate Parkinson's disease (PD).
methodsIn this 12-week crossover trial, PD patients ≥65 years of age were randomly divided into Group A (a 6-week intervention phase followed by a 6-week control phase) and Group B (a 6-week control phase followed by a 6-week intervention phase). Participants received IVGB exercise training during the intervention phase and no exercise during the control phase. Functional outcomes were measured using behavioral evaluation scales and questionnaires at baseline, week 6 and week 12.
resultsTwenty-four PD patients were included in this study, and were evenly divided into two groups. After Bonferroni adjustment, the changes in Modified Falls Efficacy Scale (MFES) and two subscales of Multi-Directional Reach Test were significantly different between two groups in the first 6-week period. In addition, the changes in Berg Balance Scale, MFES, and two subscales of Maximum Step Length were significantly different between two groups in the second 6-week period. Compared to controls, 6-week IVGB exercise intervention significantly improved different but overlapping functional outcomes in two groups of PD patients.
conclusionsThe customized IVGB exercise training improves balance, postural stability and confidence in preventing falls in older adults with mild-to-moderate PD. However, this IVGB exercise doesn't have a significant impact on quality of life.
trial registrationClinicalTrials.gov. NCT03689764 . Registered 27 September 2018, retrospectively registered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.