Evidence map›Paper›PMID 32660470›Full record

ArticleRespiratory research2020

Relationship between age and bronchodilator response at diagnosis in adult-onset asthma.

Minna Tommola, Ha-Kyeong Won, Pinja Ilmarinen, Heewon Jung, Leena E Tuomisto, Lauri Lehtimäki, Onni Niemelä, Tae-Bum Kim, Hannu Kankaanranta

Registry-linked trialOpen access · goldAbstract readComparative StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02733016 (Seinäjoki Adult Asthma Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02733016 completednot on this map

Seinäjoki Adult Asthma Study: A 12-year Real-life Follow-up Study of New-onset Asthma Diagnosed at Adult Age and Treated in Primary and Specialized Care. Finnish Title: Diagnoosista Hoitotasapainoon: Voidaanko Aikuisen Astman Hoitotasapainoa Ennustaa Diagnoosivaiheen löydösten ja Astman Ilmiasun Perusteella?

Typeobservational_patient_registrySponsorSeinajoki Central HospitalRan1999Enrolled259ConditionsAsthma
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Prevalence, Diagnostic Utility and Associated Characteristics of Bronchodilator Responsiveness.American journal of respiratory and critical care medicine · 2024
    Article
  2. Article
  3. Sex Hormones and Lung Inflammation.Advances in experimental medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Minna TommolaDepartment of Respiratory Medicine, Seinäjoki Central Hospital, Hanneksenrinne 7, FIN-60220, Seinäjoki, Finland.ORCID http://orcid.org/0000-0003-4201-389X
Ha-Kyeong WonDepartment of Internal Medicine, VHS Medical Center, Seoul, South Korea.
Pinja IlmarinenDepartment of Respiratory Medicine, Seinäjoki Central Hospital, Hanneksenrinne 7, FIN-60220, Seinäjoki, Finland.
Heewon JungDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea.
Leena E TuomistoDepartment of Respiratory Medicine, Seinäjoki Central Hospital, Hanneksenrinne 7, FIN-60220, Seinäjoki, Finland.
Lauri LehtimäkiAllergy Centre, Tampere University Hospital, Tampere, Finland.
Onni NiemeläFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Tae-Bum KimDepartment of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea. tbkim@amc.seoul.kr.
Hannu KankaanrantaDepartment of Respiratory Medicine, Seinäjoki Central Hospital, Hanneksenrinne 7, FIN-60220, Seinäjoki, Finland. hannu.kankaanranta@epshp.fi.
Seinäjoki University of Applied Sciences · FITampere University · FIUlsan College · KRSeoul Medical Center · KRTampere University of Applied Sciences · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPossible variation in bronchodilator response (BDR) according to age at the diagnosis of adult-onset asthma is unknown. Our aim was to assess if BDR in FEV

methodsA total of 1030 patients with adult-onset asthma were included; 245 from SAAS (Seinäjoki Adult Asthma Study, Finland) and 785 from COREA (Cohort for Reality and Evolution of Adult Asthma in Korea) cohorts. BDR in FEV

resultsBDR % in FEV

conclusionBy using two large cohorts of steroid-naive patients with asthma, we have shown that BDR at diagnosis of asthma is constant over large age span range, and the limit of 400 mL in BDR in FEV

trial registrationSeinäjoki Adult Asthma Study is registered at ClinicalTrials.gov with identifier number NCT02733016 .

Indexed as

Bronchial Provocation TestsBronchoconstrictionSpirometryAdministration, InhalationAdultAgedAge of OnsetAlbuterolAsthmaBronchodilator AgentsFemaleFinlandForced Expiratory VolumeHumansLungMaleAlbuterolBronchodilator AgentsAdult-onsetAsthmaAsthma-COPD overlapBronchodilator responseCohort studySpirometry

Identifiers

PMID32660470
PMCPMC7359254
OpenAlexW3040919076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.