Evidence map›Paper›PMID 32660469›Full record

ArticleBMC endocrine disorders2020

The association of erythrocyte sedimentation rate, high-sensitivity C-reactive protein and diabetic kidney disease in patients with type 2 diabetes.

Shizhe Guo, Meng Wang, Yifei Yu, Yeping Yang, Fangfang Zeng, Fei Sun, Qin Li, Min He, Yiming Li, Jie Wen and 2 more

Abstract read
In one paragraph

Article in BMC endocrine disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shizhe GuoDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Meng WangDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Yifei YuDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Yeping YangDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Fangfang ZengDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Fei SunDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Qin LiDepartment of Endocrinology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University, Shanghai, China.
Min HeDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Yiming LiDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Jie WenDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China.
Wei GongDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China. nj_gongwei2001@sina.cn.
Zhaoyun ZhangDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, 12 Wulumuqi Road, Shanghai, 200040, China. zhaoyunzhang@fudan.edu.cn.

Funding

Cultivation Project of Clinical Research of Shanghai Hospital Development Center SHDC12018X04Funding from Huashan Hospital North Affiliated to Fudan University HSBY2016004National Natural Science Foundation of China 81800720National Natural Science Foundation of China 81970716Shanghai general hospital integrated traditional Chinese and western medicine special project ZHYY-ZXYJHZX-1-01
6 · The paper itself

Abstract

backgroundTo evaluate the association between high-sensitivity C-reactive protein (hsCRP) and erythrocyte sedimentation rate (ESR), and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM).

methodsA cross-sectional study was conducted in 1210 patients with T2DM, among whom 265 had DKD. The severity of DKD was assessed by estimated-glomerular filtration rate (eGFR) and urinary albumin creatinine ratio (ACR). The relationship between ESR, hsCRP and DKD was analyzed by multivariate logistic analysis. The relationship between ESR and eGFR, ESR or ACR was analyzed by multivariate linear regression.

resultsESR (23.0 [12.0 ~ 41.5] mm/h versus 12.0 [7.0 ~ 22.0] mm/h, P <  0.001) and hsCRP (3.60 [2.20 ~ 7.65] versus 2.90 [1.80 ~ 5.60] mg/L mg/L, P <  0.01) values were significantly higher in patients with DKD than those without. Patients with higher ESR or hsCRP had lower eGFR and higher ACR. After adjusted for gender, age, hemoglobin, plasma proteins, HbA

conclusionESR was independently associated with the rate and severity of DKD in patients with T2DM.

Indexed as

Blood SedimentationAgedBiomarkersC-Reactive ProteinCross-Sectional StudiesDiabetes Mellitus, Type 2Diabetic NephropathiesFemaleFollow-Up StudiesGlomerular Filtration RateHumansMaleMiddle AgedPrognosisRetrospective StudiesSeverity of Illness IndexBiomarkersC-Reactive Protein

Identifiers

PMID32660469
PMCPMC7358197

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.