ArticleBMC musculoskeletal disorders2020
Influence of cement-augmented pedicle screws with different volumes of polymethylmethacrylate in osteoporotic lumbar vertebrae over the adjacent segments: a 3D finite element analysis.
Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 18 citations in OpenAlex.
- Multisequence MRI and clinical data-based deep learning radiomics model for predicting adjacent segment degeneration post-lumbar fusion: a retrospective multicenter study.BMC medical imaging · 2026Article
- Biomechanical effects of endoscopic ULBD in a reduced‑stiffness lumbar spine model: focus on endplate stress and hypothesis‑generating risk indicators (a finite element analysis).Scientific reports · 2026Article
- Finite element analysis of short-segment fixation combined with expandable polyetheretherketone vertebral body replacement in osteoporotic vertebrae.BMC musculoskeletal disorders · 2025Article
- Article
- Finite element analysis of endoscopic cross-overtop decompression for single-segment lumbar spinal stenosis based on real clinical cases.Frontiers in bioengineering and biotechnology · 2024Article
- Biomechanical evaluation of different posterior fixation techniques for treating thoracolumbar burst fractures of osteoporosis old patients: a finite element analysis.Frontiers in bioengineering and biotechnology · 2023Article
- Biomechanical analysis of sandwich vertebrae in osteoporotic patients: finite element analysis.Frontiers in endocrinology · 2023Article
- Impact of cage position on biomechanical performance of stand-alone lateral lumbar interbody fusion: a finite element analysis.BMC musculoskeletal disorders · 2022Article
- Biomechanical comparison between unilateral and bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures: A finite element analysis.Frontiers in bioengineering and biotechnology · 2022Article
- Risk Factors for Pulmonary Cement Embolism (PCE) After Polymethylmethacrylate Augmentation: Analysis of 32 PCE Cases.Neurospine · 2021Article
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10 authors at 2 institutions in 1 country.
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Abstract
backgroundPolymethylmethacrylate (PMMA) is commonly used for cement-augmented pedicle screw instrumentation (CAPSI) to improve the fixation stability and reduce the risk of screw loosening in the osteoporotic thoracolumbar spine. Biomechanical researches have shown that various dose of cement (1-3 ml) can be injected to enhance screw stability. To date, there have been no studies on the relationship between adjacent segment degeneration and the volume of PMMA. This study aimed to explore the influence of CAPSI with different volumes of PMMA in osteoporotic lumbar vertebrae over adjacent segments by using finite element analysis.
methodsSeven different finite element models were reconstructed and simulated under different loading conditions, including (1) an intact model, (2) three single-level CAPSI models with different volumes of PMMA (1, 1.73, and 2.5 ml), and (3) three double-level CAPSI models with different volumes of PMMA (1, 1.73, and 2.5 ml). To improve the accuracy of the finite element analysis, the models of the injectable pedicle screw and bone cement were created by using a three-dimensional scanning machine and the CAPSI patient's CT data, respectively. The range of motion (ROM), the stress of intervertebral discs, and the stress of facet in the adjacent segment were comparatively analyzed among the different models.
resultsThe ROMs of the different segments were compared with experimental data, with good agreement under the different load conditions (21.3°, 13.55°, 13.99°, and 6.11° in flexion, extension, bending, and rotation at L3-S1 level, respectively). Compared with the intact model, the ROM, disc stresses, and facet stress in adjacent segments were found to be higher in the six operative models. Otherwise, with a larger volume of PMMA injected, the ROM, disc stresses, and facet stress slightly increased at the adjacent segment. However, the differences were insignificant with the biggest difference less than 3.8%.
conclusionsCAPSI could increase the incidence of disk degeneration in the adjacent segment, while within a certain range, different volumes of PMMA provided an approximate impact over the adjacent segment degeneration.
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