ArticleBMC plant biology2020
Identification of the vernalization gene VRN-B1 responsible for heading date variation by QTL mapping using a RIL population in wheat.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 72 citations in OpenAlex.
- Integrative multi-omics analyses reveal transcriptional, metabolic, and hormonal regulation of vernalization-induced flowering in Wucai (Brassica rapa).Molecular horticulture · 2026Article
- Transcriptomic Profiling Across Developmental Stages ofMetabolites · 2026Article
- Deletion of the gene encoding the magnesium chelatase I subunit resulted in a novel wheat leaf colour mutant.Plant biotechnology journal · 2025Article
- Antagonistic effects of selection on alleles associated with seed size and seed dormancy in wheat.Genome biology · 2025Article
- A TOPLESS-related gene regulates both male and female sterility in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Pregnane derivatives in wheat (Triticum aestivum) and their potential role in generative development.Journal of plant research · 2025Article
- Mapping and validation of QTkw.cau-3DL, a major QTL controlling thousand-kernel weight in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- A gain-of-function mutation at the C-terminus of FT-D1 promotes heading by interacting with 14-3-3A and FDL6 in wheat.Plant biotechnology journal · 2025Article
- Quantitative Trait Loci Mapping of Heading Date in Wheat under Phosphorus Stress Conditions.Genes · 2024Article
- Flowering genes identification, network analysis, and database construction for 837 plants.Horticulture research · 2024Article
- Integrated Bulk Segregant Analysis, Fine Mapping, and Transcriptome Revealed QTLs and Candidate Genes Associated with Drought Adaptation in Wild Watermelon.International journal of molecular sciences · 2023Article
- Mining novel genomic regions and candidate genes of heading and flowering dates in bread wheat by SNP- and haplotype-based GWAS.Molecular breeding : new strategies in plant improvement · 2023Article
- Fine mapping and genetic analysis identified a CTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- QTL cluster analysis and marker development for kernel traits based on DArT markers in spring bread wheat (Frontiers in plant science · 2023Article
- Quick mapping and characterization of a co-located kernel length and thousand-kernel weight-related QTL in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Review
- Integrate QTL Mapping and Transcription Profiles Reveal Candidate Genes Regulating Flowering Time inFrontiers in plant science · 2022Article
- Frequent gain- and loss-of-function mutations of the BjMYB113 gene accounted for leaf color variation in Brassica juncea.BMC plant biology · 2021Article
- Transcriptome profiling of developing leaf and shoot apices to reveal the molecular mechanism and co-expression genes responsible for the wheat heading date.BMC genomics · 2021Article
- Identification of theFrontiers in plant science · 2021Article
- Genome-Wide and Exome-Capturing Sequencing of a Gamma-Ray-Induced Mutant Reveals Biased Variations in Common Wheat.Frontiers in plant science · 2021Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHeading time is one of the most important agronomic traits in wheat, as it largely affects both adaptation to different agro-ecological conditions and yield potential. Identification of genes underlying the regulation of wheat heading and the development of diagnostic markers could facilitate our understanding of genetic control of this process.
resultsIn this study, we developed 400 recombinant inbred lines (RILs) by crossing a γ-ray-induced early heading mutant (eh1) with the late heading cultivar, Lunxuan987. Bulked Segregant Analysis (BSA) of both RNA and DNA pools consisting of various RILs detected a quantitative trait loci (QTL) for heading date located on chromosomes 5B, and further genetic linkage analysis limited the QTL to a 3.31 cM region. We then identified a large deletion in the first intron of the vernalization gene VRN-B1 in eh1, and showed it was associated with the heading phenotype in the RIL population. However, it is not the mutation loci that resulted in early heading phonotype in the mutant compared to that of wildtype. RNA-seq analysis suggested that Vrn-B3 and several newly discovered genes, including beta-amylase 1 (BMY1) and anther-specific protein (RTS), were highly expressed in both the mutant and early heading pool with the dominant Vrn-B1 genotype compared to that of Lunxuan987 and late heading pool. Enrichment analysis of differentially expressed genes (DEGs) identified several key pathways previously reported to be associated with flowering, including fatty acid elongation, starch and sucrose metabolism, and flavonoid biosynthesis.
conclusionThe development of new markers for Vrn-B1 in this study supplies an alternative solution for marker-assisted breeding to optimize heading time in wheat and the DEGs analysis provides basic information for VRN-B1 regulation study.
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