Evidence map›Paper›PMID 32660355›Full record

ArticleEpigenetics2021

Expression of UDP Glucuronosyltransferases

Farideh Shafiee-Kermani, Skyla T Carney, Dereje Jima, Utibe C Utin, LaNeisha B Farrar, Melvin O Oputa, Marcono R Hines, H Karimi Kinyamu, Kevin W Trotter, Trevor K Archer and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. δ-Catenin Participates in EGF/AKT/p21International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Farideh Shafiee-KermaniCancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University , Durham, NC, USA.
Skyla T CarneyCancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University , Durham, NC, USA.
Dereje JimaBioinformatics Research Center, Ricks Hall, 1 Lampe Dr, North Carolina State University , Raleigh, NC, USA.
Utibe C UtinCancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University , Durham, NC, USA.
LaNeisha B FarrarCancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University , Durham, NC, USA.
Melvin O OputaCancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University , Durham, NC, USA.
Marcono R HinesCancer Research Program, Julius L. Chambers Biomedical/Biotechnology Research Institute, North Carolina Central University , Durham, NC, USA.
H Karimi KinyamuChromatin and Gene Expression Section, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park , NC, USA.ORCID 0000-0002-2377-7408
Kevin W TrotterChromatin and Gene Expression Section, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park , NC, USA.
Trevor K ArcherChromatin and Gene Expression Section, Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park , NC, USA.
Cathrine HoyoCenter of Human Health and the Environment, North Carolina State University , Raleigh, NC, USA.ORCID 0000-0002-2466-8617
Beverly H KollerDepartment of Genetics UNC School of Medicine, University of North Carolina at Chapel Hill , NC, USA.
Stephen J FreedlandCedars-Sinai Health System Center for Integrated Research on Cancer and Lifestyles , Cancer Genetics and Prevention Program, Surgery, Los Angeles, CA, USA.
Delores J GrantCenter of Human Health and the Environment, North Carolina State University , Raleigh, NC, USA.ORCID 0000-0001-8981-8930
North Carolina Central University · USNational Institutes of Health · USNorth Carolina State University · USCancer Genetics (United States) · USUniversity of North Carolina at Chapel Hill · US

Funding

Transcriptional Functions of Nuclear Receptors in Cancer CellsZIAES071006 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI ARCHER, TREVOR KEITH · 2009 to 2025
$58.0M
Understanding Perceptions of HIV Risk, PrEP, and PrEP use among African American Women Attending an HBCUU54MD012392 · NIMHD · NORTH CAROLINA CENTRAL UNIVERSITY · PI Cherise Baldwin Harrington · 2017 to 2026
$38.1M
The FIU Research Center in a Minority Institution (FIU-RCMI)U54MD012393 · NIMHD · FLORIDA INTERNATIONAL UNIVERSITY · PI Diana Azzam · 2017 to 2026
$32.1M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
Targeting the MEKK2-ERK5 Signaling Node in Triple Negative Breast CancerU54CA156735 · NCI · NORTH CAROLINA CENTRAL UNIVERSITY · PI RICHARDSON, MICHELER RICARDO · 2010 to 2021
$13.0M
v-Ha-ras Transgene Expression in TgAC MiceS06GM008049 · NIGMS · NORTH CAROLINA CENTRAL UNIVERSITY · PI RUDD, M AUDREY · 1989 to 2009
$5.7M
NCI NIH HHS U54 CA156735NIEHS NIH HHS P30 ES025128NIGMS NIH HHS S06 GM008049NIMHD NIH HHS U54 MD012392NIMHD NIH HHS U54 MD012393
6 · The paper itself

Abstract

Studies have suggested that abrogated expression of detoxification enzymes, UGT2B15 and UGT2B17, are associated with prostate tumour risk and progression. We investigated the role of EGF on the expression of these enzymes since it interacts with signalling pathways to also affect prostate tumour progression and is additionally associated with decreased DNA methylation. The expression of

Indexed as

DNA MethylationGlucuronosyltransferaseProstatic NeoplasmsGene Expression Regulation, NeoplasticHumansMaleMinor Histocompatibility AntigensGlucuronosyltransferaseMinor Histocompatibility AntigensUDP-glucuronosyltransferase 2B15, humanUGT2B17 protein, humanDNA methyltransferasesepigenetic regulationHuman UDP-glucuronosyltransferases 2Bmethylationprostate cancer

Identifiers

PMID32660355
PMCPMC7901543
OpenAlexW3042712781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.