Evidence map›Paper›PMID 32660310›Full record

SynthesisJournal of the American Heart Association2020

Coronary Flow Capacity to Identify Stenosis Associated With Coronary Flow Improvement After Revascularization: A Combined Analysis From DEFINE FLOW and IDEAL.

Tadashi Murai, Valérie E Stegehuis, Tim P van de Hoef, Gilbert W M Wijntjens, Masahiro Hoshino, Yoshihisa Kanaji, Tomoyo Sugiyama, Rikuta Hamaya, Sukhjinder S Nijjer, Guus A de Waard and 12 more

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Coronary flow capacity: where to next?EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 5 countries.

Tadashi MuraiHeart Center Amsterdam UMC Amsterdam The Netherlands.
Valérie E StegehuisHeart Center Amsterdam UMC Amsterdam The Netherlands.
Tim P van de HoefHeart Center Amsterdam UMC Amsterdam The Netherlands.
Gilbert W M WijntjensHeart Center Amsterdam UMC Amsterdam The Netherlands.
Masahiro HoshinoDepartment of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.
Yoshihisa KanajiDepartment of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.
Tomoyo SugiyamaDepartment of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.
Rikuta HamayaDepartment of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.
Sukhjinder S NijjerDepartment of Cardiology Hammersmith Hospital Imperial College Healthcare NHS Trust London United Kingdom.
Guus A de WaardDepartment of Cardiology Nuclear Medicine & PET Research Amsterdam UMCVrije Universiteit Amsterdam The Netherlands.
Mauro Echavarria-PintoDepartment of Cardiology Hospital General ISSSTE Querétaro México.
Paul KnaapenDepartment of Cardiology Nuclear Medicine & PET Research Amsterdam UMCVrije Universiteit Amsterdam The Netherlands.
Martijn MeuwissenDepartment of Cardiology Amphia Hospital Breda The Netherlands.
Justin E DaviesDepartment of Cardiology Hammersmith Hospital Imperial College Healthcare NHS Trust London United Kingdom.
Niels van RoyenDepartment of Cardiology Radboud University Medical Center Nijmegen The Netherlands.
Javier EscanedDepartment of Cardiology Hospital Clinico San Carlos IDISSC, and Universidad Complutense de Madrid Madrid Spain.
Maria SiebesDepartment of Biomedical Engineering and Physics Amsterdam Cardiovascular Sciences Amsterdam UMC University of Amsterdam The Netherlands.
Richard L KirkeeideDivision of Cardiology Department of Medicine Weatherhead PET Imaging Center University of Texas Medical School and Memorial Hermann Hospital Houston TX.
K Lance GouldDivision of Cardiology Department of Medicine Weatherhead PET Imaging Center University of Texas Medical School and Memorial Hermann Hospital Houston TX.
Nils P JohnsonDivision of Cardiology Department of Medicine Weatherhead PET Imaging Center University of Texas Medical School and Memorial Hermann Hospital Houston TX.
Jan J PiekHeart Center Amsterdam UMC Amsterdam The Netherlands.
Tsunekazu KakutaDepartment of Cardiovascular Medicine Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki Japan.
Amsterdam University Medical Centers · NLTsuchiura Kyodo General Hospital · JPMemorial Hermann · USImperial College Healthcare NHS Trust · GBAmphia Ziekenhuis · NLRadboud University Nijmegen · NLUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Coronary flow capacity (CFC), which is a categorical assessment based on the combination of hyperemic coronary flow and coronary flow reserve (CFR), has been introduced as a comprehensive assessment of the coronary circulation to overcome the limitations of CFR alone. The aim of this study was to quantify coronary flow changes after percutaneous coronary intervention in relation to the classification of CFC and the current physiological cutoff values of fractional flow reserve, instantaneous wave-free ratio, and CFR. Methods and Results Using the combined data set from DEFINE FLOW (Distal Evaluation of Functional Performance With Intravascular Sensors to Assess the Narrowing Effect -Combined Pressure and Doppler FLOW Velocity Measurements) and IDEAL (Iberian-Dutch-English), a total of 133 vessels that underwent intracoronary Doppler flow measurement before and after percutaneous coronary intervention were analyzed. CFC classified prerevascularization lesions as normal (14), mildly reduced (40), moderately reduced (31), and severely reduced (48). Lesions with larger impairment of CFC showed greater increase in coronary flow and vice versa (median percent increase in coronary flow by revascularization: 4.2%, 25.9%, 50.1%, and 145.5%, respectively;

Indexed as

Coronary AngiographyCoronary CirculationCoronary StenosisPercutaneous Coronary InterventionHumansMulticenter Studies as Topiccoronary blood flowcoronary flow capacitycoronary flow reservefractional flow reservepercutaneous coronary intervention

Identifiers

PMID32660310
PMCPMC7660740
OpenAlexW3042415530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.