Evidence map›Paper›PMID 32660294›Full record

ArticleRenal failure2020

SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement therapy.

Hai Wang, Xiao Kang, Yu Shi, Zheng-Hai Bai, Jun-Hua Lv, Jiang-Li Sun, Hong Hong Pei

Open access · goldAbstract read
In one paragraph

Article in Renal failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hai WangEmergency Department and EICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.
Xiao KangEmergency Department and EICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.
Yu ShiEmergency Department and EICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.
Zheng-Hai BaiEmergency Department and EICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.
Jun-Hua LvEmergency Department and EICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.
Jiang-Li SunEmergency Department and EICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.
Hong Hong PeiEmergency Department and EICU, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, PR China.
Second Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is the most common cause of organ failure in multiple organ dysfunction syndrome (MODS) and is associated with increased mortality. This study aimed at determining the efficacy of sequential organ failure assessment (SOFA), and acute physiology and chronic health evaluation II (APACHE-II) scoring systems in assessing the prognosis of critically ill patients with AKI undergoing CRRT.

methodsThe predictive value of SOFA and APACHE-II scores for 28- and 90-d mortality in patients with AKI undergoing continuous renal replacement therapy (CRRT) were determined by multivariate analysis, sensitivity analysis, and curve-fitting analysis.

resultsA total of 836 cases were included in this study. Multivariate Cox logistic regression analysis showed that SOFA scores were associated with 28- and 90-d mortality in patients with AKI undergoing CRRT. The adjusted HR of SOFA for28-d mortality were 1.18 (1.14, 1.21), 1.24 (1.18, 1.31), and 1.19 (1.13, 1.24) in the three models, respectively, and the adjusted HR of SOFA for 90-d mortality was 1.12 (1.09, 1.16), 1.15 (1.10, 1.19), and 1.15 (1.10, 1.19), respectively. The subgroup analysis showed that the SOFA score was associated with 28-d and 90-d mortality in patients with AKI undergoing CRRT. APACHE-II score was not associated with 28- and 90-d mortality patients with AKI undergoing CRRT. Curve fitting analysis showed that SOFA scores increased had a higher prediction accuracy for 28- and 90-d than APACHE-II.

conclusionsThe SOFA score showed a higher accuracy of mortality prediction in critically ill patients with AKI undergoing CRRT than the APACHE-II score.

Indexed as

APACHEOrgan Dysfunction ScoresAcute Kidney InjuryAdultAgedChinaContinuous Renal Replacement TherapyCritical IllnessFemaleHumansIntensive Care UnitsLogistic ModelsMaleMiddle AgedMultivariate AnalysisPredictive Value of Testsacute kidney injuryAPACHE-II scorecontinuous renal replacement therapySOFA score

Identifiers

PMID32660294
PMCPMC7470067
OpenAlexW3042742870

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.