Evidence map›Paper›PMID 32660250›Full record

ArticleThe journal of physical chemistry. B2020

Dehydrogenase Binding Sites Abolish the "Dark" Fraction of NADH: Implication for Metabolic Sensing via FLIM.

Simin Cao, Haoyang Li, Yangyi Liu, Mengyu Wang, Mengjie Zhang, Sanjun Zhang, Jinquan Chen, Jianhua Xu, Jay R Knutson, Ludwig Brand

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry. B, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Label-Free Optical Metabolic Imaging in Cells and Tissues.Annual review of biomedical engineering · 2023
    Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Simin CaoState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.
Haoyang LiState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.
Yangyi LiuState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.
Mengyu WangState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.
Mengjie ZhangState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.
Sanjun ZhangState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.ORCID 0000-0002-7377-2429
Jinquan ChenState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.ORCID 0000-0003-0652-1379
Jianhua XuState Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062, China.ORCID 0000-0001-7585-3014
Jay R KnutsonLaboratory for Advanced Microscopy and Biophotonics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, United States.
Ludwig BrandDepartment of Biology, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218, United States.
East China Normal University · CNJohns Hopkins University · USNational Institutes of Health · US

Funding

Multiphoton Microscopy DevelopmentZIAHL006065 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KNUTSON, JAY R · 2010 to 2025
$11.4M
Time Resolved Fluorescence SpectroscopyZIAHL001452 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KNUTSON, JAY R · 2009 to 2025
$5.1M
Intramural NIH HHS ZIA HL001452Intramural NIH HHS ZIA HL006065
6 · The paper itself

Abstract

The fluorescence of dinucleotide NADH has been exploited for decades to determine the redox state of cells and tissues

Indexed as

Dinucleoside PhosphatesNADBinding SitesMicroscopy, FluorescenceOxidoreductasesDinucleoside PhosphatesNADOxidoreductases

Identifiers

PMID32660250
PMCPMC7477841
OpenAlexW3042245365

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.