Evidence map›Paper›PMID 32660137›Full record

ArticleInternational journal of molecular sciences2020

Temporal TGF-β Supergene Family Signalling Cues Modulating Tissue Morphogenesis: Chondrogenesis within a Muscle Tissue Model?

Fei Xiong, Jörg Hausdorf, Thomas R Niethammer, Volkm Ar Jansson, Roland M Klar

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fei XiongDepartment of Orthopedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, 81377 Munich, Germany.ORCID 0000-0003-2124-5763
Jörg HausdorfDepartment of Orthopedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, 81377 Munich, Germany.
Thomas R NiethammerDepartment of Orthopedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, 81377 Munich, Germany.
Volkm Ar JanssonDepartment of Orthopedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, 81377 Munich, Germany.
Roland M KlarDepartment of Orthopedics, Physical Medicine and Rehabilitation, University Hospital, LMU Munich, 81377 Munich, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

China Scholarship Council 201706920036Friedrich-Baur-Stiftung CaMuTeFriedrich-Baur-Stiftung Lite:P
6 · The paper itself

Abstract

Temporal translational signalling cues modulate all forms of tissue morphogenesis. However, if the rules to obtain specific tissues rely upon specific ligands to be active or inactive, does this mean we can engineer any tissue from another? The present study focused on the temporal effect of "multiple" morphogen interactions on muscle tissue to figure out if chondrogenesis could be induced, opening up the way for new tissue models or therapies. Gene expression and histomorphometrical analysis of muscle tissue exposed to rat bone morphogenic protein 2 (rBMP-2), rat transforming growth factor beta 3 (rTGF-β

Indexed as

AnimalsBone Morphogenetic Protein 2Bone Morphogenetic Protein 7ChondrogenesisCuesGene ExpressionMaleMorphogenesisMusclesRatsRats, Inbred F344Signal TransductionTransforming Growth Factor beta3Bone Morphogenetic Protein 2Bone Morphogenetic Protein 7Transforming Growth Factor beta3BMP-2BMP-7chondrogenesismorphogen combinationsmuscle tissuetemporal modulationTGF-β3tissue morphogenesis

Identifiers

PMID32660137
PMCPMC7402331
OpenAlexW3040933612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.