Evidence map›Paper›PMID 32660103›Full record

ArticleCells2020

Toxicoproteomic Profiling of

Christopher Trent Brewer, Kiran Kodali, Jing Wu, Timothy I Shaw, Junmin Peng, Taosheng Chen

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Christopher Trent BrewerDepartment of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Kiran KodaliCenter for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Jing WuDepartment of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Timothy I ShawCenter for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Junmin PengCenter for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Taosheng ChenDepartment of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
St. Jude Children's Research Hospital · US

Funding

Regulation of xenobiotic receptors PXR and CAR: implications in drug dispositionR35GM118041 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Taosheng Chen · 2016 to 2026
$4.3M
Multi-level Integrative Proteomics to Alzheimer's Disease PathwaysR01AG053987 · NIA · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI PENG, JUNMIN · 2016 to 2020
$2.2M
hPXR antagonism in Anti-TB hepatotoxicityF31DK116523 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI BREWER, CHRISTOPHER TRENT · 2017 to 2017
$25k
NIA NIH HHS R01 AG053987NIDDK NIH HHS F31 DK116523NIGMS NIH HHS R35 GM118041
6 · The paper itself

Abstract

Tuberculosis is a global health threat that affects millions of people every year, and treatment-limiting toxicity remains a considerable source of treatment failure. Recent reports have characterized the nature of

Indexed as

AnimalsAntitubercular AgentsChemical and Drug Induced Liver InjuryCytochrome P-450 Enzyme SystemHemeHomocysteineIron-Sulfur ProteinsIsoniazidLiverMiceMice, Inbred C57BLNiacinamideOxidative StressProteomeRifampinVitamin B 6Antitubercular AgentsCytochrome P-450 Enzyme SystemHemeHomocysteineIron-Sulfur ProteinsIsoniazidNiacinamideProteomeRifampinVitamin B 6anemiaantitubercular therapycytochrome P450drug-induced liver injuryheme biosynthesishypercoagulabilityiron–sulfur clusterpellagravitamin B3vitamin B6

Identifiers

PMID32660103
PMCPMC7407182
OpenAlexW3042199459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.