Evidence map›Paper›PMID 32659912›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Mayara Nunes Vitor Anjos, Luiz Nascimento de Araújo-Neto, Maria Daniela Silva Buonafina, Rejane Pereira Neves, Edson Rubhens de Souza, Isabelle Cristinne Ferraz Bezerra, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares, Henrique Douglas Melo Coutinho, Natália Martins and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Mayara Nunes Vitor AnjosLaboratory of Natural Products, Department of Biochemistry, Federal University of Pernambuco, Recife 50670-901, Brazil.
Luiz Nascimento de Araújo-NetoLaboratory of Medical Mycology, Department of Mycology, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0002-6814-4647
Maria Daniela Silva BuonafinaLaboratory of Medical Mycology, Department of Mycology, Federal University of Pernambuco, Recife 50670-901, Brazil.
Rejane Pereira NevesLaboratory of Medical Mycology, Department of Mycology, Federal University of Pernambuco, Recife 50670-901, Brazil.
Edson Rubhens de SouzaLaboratory of Medical Mycology, Department of Mycology, Federal University of Pernambuco, Recife 50670-901, Brazil.
Isabelle Cristinne Ferraz BezerraLaboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife 50670-901, Brazil.
Magda Rhayanny Assunção FerreiraLaboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0001-8668-6223
Luiz Alberto Lira SoaresLaboratory of Pharmacognosy, Department of Pharmaceutical Sciences, Federal University of Pernambuco, Recife 50670-901, Brazil.
Henrique Douglas Melo CoutinhoLaboratory of Microbiology and Molecular Biology, Department of Biological Chemistry, Regional University of Cariri, Crato 63000-000, Brazil.ORCID 0000-0002-6634-4207
Natália MartinsFaculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.ORCID 0000-0002-5934-5201
Márcia Vanusa da SilvaLaboratory of Natural Products, Department of Biochemistry, Federal University of Pernambuco, Recife 50670-901, Brazil.
Maria Tereza Dos Santos CorreiaLaboratory of Natural Products, Department of Biochemistry, Federal University of Pernambuco, Recife 50670-901, Brazil.
Universidade Federal de Pernambuco · BRUniversidade do Porto · PTUniversidade Regional do Cariri · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOpportunistic fungal infections are increasingly common, with

methodsMinimal inhibitory concentrations (MIC) were determined by broth microdilution technique, and the mechanism of action was assessed by ergosterol, sorbitol, cell viability, reactive oxygen species (ROS) generation and phosphatidylserine externalization tests.

resultsAll the tested extracts evidenced antifungal activity, but the methanol extract was revealed to be the most effective (MIC = 3.12 μg/mL) on

conclusion

Indexed as

anti-candida activitymechanism of actionnatural productsOcotea glomerata

Identifiers

PMID32659912
PMCPMC7400089
OpenAlexW3041487777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.