Evidence map›Paper›PMID 32659907›Full record

ArticleNanomaterials (Basel, Switzerland)2020

The Effects of In Vivo Exposure to Copper Oxide Nanoparticles on the Gut Microbiome, Host Immunity, and Susceptibility to a Bacterial Infection in Earthworms.

Elmer Swart, Jiri Dvorak, Szabolcs Hernádi, Tim Goodall, Peter Kille, David Spurgeon, Claus Svendsen, Petra Prochazkova

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  6. Review
  7. Review
  8. Article
  9. The Impact of Nanoparticles on Innate Immune Activation by Live Bacteria.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Elmer SwartUK Centre for Ecology and Hydrology, Maclean Building, Benson Lane, Wallingford OX10 8BB, UK.ORCID 0000-0002-8269-1700
Jiri DvorakLaboratory of Cellular and Molecular Immunology, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague 4, Czech Republic.ORCID 0000-0002-3714-7781
Szabolcs HernádiSchool of Biosciences, Cardiff University, Sir Martin Evans Building, Museum Avenue, Cardiff CF10 3AX, UK.
Tim GoodallUK Centre for Ecology and Hydrology, Maclean Building, Benson Lane, Wallingford OX10 8BB, UK.ORCID 0000-0002-1526-4071
Peter KilleSchool of Biosciences, Cardiff University, Sir Martin Evans Building, Museum Avenue, Cardiff CF10 3AX, UK.
David SpurgeonUK Centre for Ecology and Hydrology, Maclean Building, Benson Lane, Wallingford OX10 8BB, UK.
Claus SvendsenUK Centre for Ecology and Hydrology, Maclean Building, Benson Lane, Wallingford OX10 8BB, UK.
Petra ProchazkovaLaboratory of Cellular and Molecular Immunology, Institute of Microbiology of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague 4, Czech Republic.ORCID 0000-0002-8881-971X
UK Centre for Ecology & Hydrology · GBCardiff University · GBCzech Academy of Sciences · CZ

Funding

Horizon 2020 671881
6 · The paper itself

Abstract

Nanomaterials (NMs) can interact with the innate immunity of organisms. It remains, however, unclear whether these interactions can compromise the immune functioning of the host when faced with a disease threat. Co-exposure with pathogens is thus a powerful approach to assess the immuno-safety of NMs. In this paper, we studied the impacts of in vivo exposure to a biocidal NM on the gut microbiome, host immune responses, and susceptibility of the host to a bacterial challenge in an earthworm.

Indexed as

copperearthwormsEisenia fetidainfectioninnate immunitymicrobiomenanomaterialsnanoparticlessurvival

Identifiers

PMID32659907
PMCPMC7408611
OpenAlexW3041513499

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.