ArticleAntibiotics (Basel, Switzerland)2020
Oxytetracycline Pharmacokinetics After Intramuscular Administration in Cows with Clinical Metritis Associated with
Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- PknB and STP as potential targets of luteolin in combating Trueperella pyogenes infections.Scientific reports · 2025Article
- Determination of pharmacokinetic-pharmacodynamic cutoff values of oxytetracycline in calves and adult cattle using population pharmacokinetic modeling.Frontiers in microbiology · 2024Article
- Allogenic adipose derived mesenchymal stem cells are effective than antibiotics in treating endometritis.Scientific reports · 2023Article
- Population Pharmacokinetics of Doxycycline, Administered Alone or with N-Acetylcysteine, in Chickens with ExperimentalPharmaceutics · 2022Article
- Optimization of Veterinary Antimicrobial Treatment in Companion and Food Animals.Antibiotics (Basel, Switzerland) · 2022Article
- Oxytetracycline Persistence in Uterine Secretion after Intrauterine Administration in Cows with Metritis.Animals : an open access journal from MDPI · 2022Article
- Validation of a single liquid chromatography-tandem mass spectrometry approach for oxytetracycline determination in bull plasma, seminal plasma and urine.Drug testing and analysis · 2022Article
- Antimicrobial Resistance in Equine Reproduction.Animals : an open access journal from MDPI · 2021Review
- Molecular Characterization of Antimicrobial Resistance and Virulence Genes of Bacterial Pathogens from Bovine and Caprine Mastitis in Northern Lebanon.Microorganisms · 2021Article
- Article
- Antimicrobial Resistance inAntibiotics (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic therapy with oxytetracycline is often used for treatment of clinical metritis although data about its penetration into the uterus and uterine secretion are lacking. Uterine secretions and milk from six cows with clinical metritis were collected for microbiological assay. The animals were treated intramuscularly with long-acting oxytetracycline (20 mg/kg) and samples of plasma, milk and uterine secretions were collected for determination of the antibiotic concentrations by HPLC-PDA analysis. Pharmacokinetics of the antibiotic and in silico prediction of its penetration into the uterus were described.
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Registered trials
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