Evidence map›Paper›PMID 32659891›Full record

Trial reportNutrients2020

Effect of Vitamin D Supplementation on Inflammatory Markers in Non-Obese Lebanese Patients with Type 2 Diabetes: A Randomized Controlled Trial.

Cynthia El Hajj, Stéphane Walrand, Mariana Helou, Kaissar Yammine

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03782805 (Effect of Vitamin D Treatment on Some Inflammatory Markers in Non-obese Lebanese Patients With Type 2 Diabetes), which is not on this map. Cited by 32 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 11 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03782805 nacompletednot on this map

Effect of Vitamin D Treatment on Some Inflammatory Markers in Non-obese Lebanese Patients With Type 2 Diabetes

TypeinterventionalSponsorUniversité d'AuvergneRan2018 to 2018Enrolled88ConditionsVitamin D Deficiency, Type2 DiabetesArmscholecalciferol (Euro-Pharm International, Canada), Placebo tablet
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 11 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Cynthia El HajjDepartment of Nutrition, Faculty of Natural Sciences, Lebanese American University, Beirut 1102 2801, Lebanon.
Stéphane WalrandUnité de Nutrition Humaine, France Clermont Université, Université d'Auvergne, INRA, UMR 1019, UNH, CRNH Auvergne, 63009 Clermont-Ferrand, France.
Mariana HelouDepartment of Medicine, School of Medicine, Lebanese American University, Beirut 1102, Lebanon.
Kaissar YammineDepartment of Orthopedic Surgery, Lebanese American University School of Medecine-Rizk Hospital, Beirut, Lebanon-Center for Evidence-Based Anatomy, Sports & Orthopedic Research, Jdeideh 1102, Lebanon.
Lebanese American University · LBUnité de Nutrition Humaine · FRUniversité Clermont Auvergne · FRUniversity Medical Center Rizk Hospital · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA low serum 25-hydroxyvitamin D (25(OH) D) concentration has been associated with a higher risk of type 2 diabetes mellitus (T2DM), especially in older people. Our aim in this randomized controlled trial was to evaluate the effect of vitamin D treatment on inflammatory markers in non-obese Lebanese patients with T2DM, living in Beirut, Lebanon.

methodsNon-Obese patients with T2DM (

resultsThe vitamin D group showed higher blood levels of (25(OH) D) (

conclusionSix months of vitamin D supplementation led to a decrease in some inflammatory markers in patients with T2DM. Additional studies with a larger sample and a longer period are advised in this regard. This trial was registered at ClinicalTrial.gov; Identifier number: NCT03782805.

Indexed as

AgedBlood GlucoseCholecalciferolC-Reactive ProteinDiabetes Mellitus, Type 2Dietary SupplementsFemaleHumansInsulin ResistanceInterleukin-6LebanonMaleTumor Necrosis Factor-alphaVitamin DVitamin D DeficiencyVitamins25-hydroxyvitamin DBlood GlucoseCholecalciferolC-Reactive ProteinIL6 protein, humanInterleukin-6Tumor Necrosis Factor-alphaVitamin DVitaminshs-CRPIL-6TNF-αtype 2 diabetes mellitusvitamin D

Identifiers

PMID32659891
PMCPMC7400886
OpenAlexW3041106954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.