ReviewEuropean surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes2020
Intraoperative Imaging Techniques to Visualize Hepatic (Micro)Perfusion: An Overview.
Review in European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Non-Invasive Prediction of Microvessel Density in Pediatric Hepatoblastoma Using Contrast-Enhanced Ultrasound Quantitative Parameters.Diagnostics (Basel, Switzerland) · 2025Article
- The physiological basis for individualized oxygenation targets in critically ill patients with circulatory shock.Intensive care medicine experimental · 2024Review
- Microcirculation-driven mitochondrion dysfunction during the progression of experimental sepsis.Scientific reports · 2024Article
- Predicting early graft loss in pancreas transplantation using novel imaging techniques: are we there yet?Hepatobiliary surgery and nutrition · 2023Article
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Authors and funding
7 authors.
Funding
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Abstract
The microcirculation plays a crucial role in the distribution of perfusion to organs. Studies have shown that microcirculatory dysfunction is an independent predictor of morbidity and mortality. Hence, assessment of liver perfusion offers valuable information on the (patho)physiological state of the liver. The current review explores techniques in perfusion imaging that can be used intraoperatively. Available modalities include dynamic contrast-enhanced ultrasound, handheld vital microscopes, indocyanine green fluorescence angiography, and laser contrast speckle imaging. Dynamic contrast-enhanced ultrasound relays information on deep tissue perfusion and is a commonly used technique to assess tumor perfusion. Handheld vital microscopes provide direct visualization of the sinusoidal architectural structure of the liver, which is a unique feature of this technique. Intraoperative fluorescence imaging uses indocyanine green, a dye that is administered intravenously to visualize microvascular perfusion when excited using near-infrared light. Laser speckle contrast imaging produces non-contact large surface-based tissue perfusion imaging free from movement- or pressure-related artefacts. In this review, we discuss the intrinsic advantages and disadvantages of these techniques and their clinical and/or scientific applications.
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