Evidence map›Paper›PMID 32659462›Full record

ArticleThrombosis research2020

Coronavirus disease 2019 (COVID-19) associated coagulopathy and its impact on outcomes in Shenzhen, China: A retrospective cohort study.

Ying-Yi Luan, Yan Liu, Xue-Yan Liu, Bao-Jun Yu, Rong-Ling Chen, Mian Peng, Di Ren, Hao-Li Li, Lei Huang, Yong Liu and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Thrombosis research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Ying-Yi LuanDepartment of Critical Care Medicine and Infection Prevention and Control, The Second People's Hospital of Shenzhen & First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen, People's Republic of China.
Yan LiuDepartment of Critical Care Medicine and Infection Prevention and Control, The Second People's Hospital of Shenzhen & First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen, People's Republic of China.
Xue-Yan LiuDepartment of Critical Care Medicine, Shenzhen People's Hospital, Shenzhen, People's Republic of China.
Bao-Jun YuDepartment of Critical Care Medicine, Bao'an People's Hospital, Shenzhen, People's Republic of China.
Rong-Ling ChenDepartment of Critical Care Medicine, Central People's Hospital of Longgang, Shenzhen, People's Republic of China.
Mian PengDepartment of Critical Care Medicine, the Third Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen, People's Republic of China.
Di RenDepartment of Critical Care Medicine and Infection Prevention and Control, The Second People's Hospital of Shenzhen & First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen, People's Republic of China.
Hao-Li LiDepartment of Critical Care Medicine and Infection Prevention and Control, The Second People's Hospital of Shenzhen & First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen, People's Republic of China.
Lei HuangDepartment of Critical Care Medicine, Peking University Shenzhen Hospital, Shenzhen, People's Republic of China.
Yong LiuDepartment of Critical Care Medicine, Shenzhen Hospital of Southern Medical University, Shenzhen, People's Republic of China.
Jin-Xiu LiDepartment of Critical Care Medicine, The Third People's Hospital of Shenzhen, Shenzhen, People's Republic of China.
Yong-Wen FengDepartment of Critical Care Medicine and Infection Prevention and Control, The Second People's Hospital of Shenzhen & First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen, People's Republic of China. Electronic address: fengyongwen2008@126.com.
Ming WuDepartment of Critical Care Medicine and Infection Prevention and Control, The Second People's Hospital of Shenzhen & First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen, People's Republic of China. Electronic address: boshiyy@126.com.
Shenzhen University Health Science Center · CNSouthern Medical University Shenzhen Hospital · CNLonggang Central Hospital · CNPeking University Shenzhen Hospital · CNShenZhen People’s Hospital · CNShenzhen Third People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly detection of suspected critical patients infected with coronavirus disease 2019 (COVID-19) is very important for the treatment of patients. This study aimed to investigate the role of COVID-19 associated coagulopathy (CAC) to preview and triage. METHODS AND

resultsA cohort study was designed from government designated COVID-19 treatment center. CAC was defined as International Society on Thrombosis and Haemostasis (ISTH) score ≥2. Data from 117 patients COVID-19 were reviewed on admission. The primary and secondary outcomes were admission to Intensive Care Unit (ICU), the use of mechanical ventilation, vital organ dysfunction, discharges of days 14, 21 and 28 from admission and hospital mortality. Among them, admission to ICU was increased progressively from 16.1% in patients with non-CAC to 42.6% in patients with CAC (P < 0.01). Likely, invasive ventilation and noninvasive ventilation were increased from 1.8%, 21.4% in patients with non-CAC to 21.3%, 52.5% in patients with CAC, respectively (P < 0.01). The incidences of acute hepatic injury and acute respiratory distress syndrome in non-CAC and CAC were 28.6% vs. 62.3%, 8.9% vs. 27.9%, respectively (P < 0.01). The discharges of days 14, 21 and 28 from admission were more in non-CAC than those of CAC (P < 0.05). Multiple logistic regression results showed that ISTH score ≥2 was obviously associated with the admission to ICU (OR 4.07, 95% CI 1.47-11.25 P = 0.007) and the use of mechanical ventilation (OR 5.54, 95% CI 2.01-15.28 P = 0.001) in patients with COVID-19.

conclusionAll results show ISTH score ≥2 is an important indicator to preview and triage for COVID-19 patients.

Indexed as

AdultAgedAged, 80 and overBetacoronavirusChinaCoronavirus InfectionsCOVID-19Disseminated Intravascular CoagulationFemaleHospitalizationHumansIntensive Care UnitsMaleMiddle AgedPandemicsPneumonia, ViralCoagulopathyCoronavirus disease 2019ISTH scoreMechanical ventilationOutcome

Identifiers

PMID32659462
PMCPMC7347306
OpenAlexW3041443798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.