ArticleJournal of the American Chemical Society2020
Silver-Catalyzed Enantioselective Propargylic C-H Bond Amination through Rational Ligand Design.
Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed.
- Highly Stereoselective Addition of β-Borylenamides to Aldehydes Enabled by Late‑Stage Ligand Modification.Angewandte Chemie (International ed. in English) · 2026Article
- Article
- Enantioselectivity in Transition Metal Catalyzed Propargylic Substitution Reactions: A Theoretical Perspective.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Silver-Catalyzed C(spACS organic & inorganic Au · 2026Review
- Copper-Mediated Divergent Reactivity of Allene-Tethered Carbamates under Radical Conditions.Organic letters · 2025Article
- Catalytic Metalloradical System for Radical 1,6-C(spJournal of the American Chemical Society · 2025Article
- An Organometallic Umpolung Approach for Iron-Mediated Propargylic C-H Etherification.Angewandte Chemie (International ed. in English) · 2024Article
- Transition Metal Mimetic π-Activation by Cationic Bismuth(III) Catalysts for Allylic C-H Functionalization of Olefins Using C═O and C═N Electrophiles.Journal of the American Chemical Society · 2024Article
- Enantioselective and Regiodivergent Synthesis of Propargyl- and Allenylsilanes through Catalytic Propargylic C-H Deprotonation.Angewandte Chemie (International ed. in English) · 2024Article
- Chemo- and enantioselective intramolecular silver-catalyzed aziridinations of carbamimidates.Chemical communications (Cambridge, England) · 2023Article
- Catalytic, asymmetric carbon-nitrogen bond formation using metal nitrenoids: from metal-ligand complexesChemical science · 2023Review
- Copper-catalyzed propargylic C-H functionalization for allene syntheses.Chemical science · 2023Article
- Silver Catalyzed Site-Selective C(spMolecules (Basel, Switzerland) · 2022Article
- Enantioselective and Diastereodivergent Allylation of Propargylic C-H Bonds.Journal of the American Chemical Society · 2022Article
- Combining visible-light induction and copper catalysis for chemo-selective nitrene transfer for late-stage amination of natural products.Communications chemistry · 2022Article
- Stereoretentive and regioselective selenium-catalyzed intermolecular propargylic C-H amination of alkynes.Chemical science · 2022Article
- Biocatalytic, Intermolecular C-H Bond Functionalization for the Synthesis of Enantioenriched Amides.Angewandte Chemie (International ed. in English) · 2021Article
- Nitrene transfer catalysts for enantioselective C-N bond formation.Nature reviews. Chemistry · 2021Review
- Silver-Catalyzed Enantioselective Sulfimidation Mediated by Hydrogen Bonding Interactions.Angewandte Chemie (International ed. in English) · 2021Article
- Gold-catalysed asymmetric net addition of unactivated propargylic C-H bonds to tethered aldehydes.Nature catalysis · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
Asymmetric C-H amination via nitrene transfer is a powerful tool to prepare enantioenriched amine precursors from abundant C-H bonds. Herein, we report a regio- and enantioselective synthesis of γ-alkynyl γ-aminoalcohols via a silver-catalyzed propargylic C-H amination. The protocol was enabled by a new bis(oxazoline) (BOX) ligand designed via a rapid structure-activity relationship (SAR) analysis. The method utilizes accessible carbamate esters bearing γ-propargylic C-H bonds and furnishes versatile products in good yields and excellent enantioselectivity (90-99%
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.