Evidence map›Paper›PMID 32659039›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Proapoptotic Peptide Brush Polymer Nanoparticles via Photoinitiated Polymerization-Induced Self-Assembly.

Hao Sun, Wei Cao, Nanzhi Zang, Tristan D Clemons, Georg M Scheutz, Ziying Hu, Matthew P Thompson, Yifei Liang, Maria Vratsanos, Xuhao Zhou and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 70 citations in OpenAlex.

  1. Polymerization-Induced Self-Assembly of Nonlinear Polymers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
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  20. Constructing helical nanowiresRSC advances · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Hao SunDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0001-9153-4021
Wei CaoDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0002-5048-7991
Nanzhi ZangDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Tristan D ClemonsDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Georg M ScheutzGeorge & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.
Ziying HuDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Matthew P ThompsonDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Yifei LiangDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0002-4841-3491
Maria VratsanosDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0001-8377-4113
Xuhao ZhouDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.
Wonmin ChoiDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0002-8305-9133
Brent S SumerlinGeorge & Josephine Butler Polymer Research Laboratory, Center for Macromolecular Science & Engineering, Department of Chemistry, University of Florida, Gainesville, FL, 32611, USA.ORCID 0000-0001-5749-5444
Samuel I StuppDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0002-5491-7442
Nathan C GianneschiDepartment of Chemistry, Department of Materials Science & Engineering, Department of Biomedical Engineering, Northwestern University, Evanston, IL, 60208, USA.ORCID 0000-0001-9945-5475
Northwestern University · USUniversity of Florida · US

Funding

MMP responsive polymeric materials for treating acute myocardial infarctionR01HL139001 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Karen L Christman, Nathan Claude Gianneschi · 2017 to 2026
$3.9M
NHLBI NIH HHS R01 HL139001
6 · The paper itself

Abstract

Herein, we report the photoinitiated polymerization-induced self-assembly (photo-PISA) of spherical micelles consisting of proapoptotic peptide-polymer amphiphiles. The one-pot synthetic approach yielded micellar nanoparticles at high concentrations and at scale (150 mg mL

Indexed as

ApoptosisLightAmino Acid SequenceCell SurvivalHeLa CellsHumansHydrophobic and Hydrophilic InteractionsMicellesNanoparticlesPeptidesPolymerizationPolymersMicellesPeptidesPolymersnanoparticlespeptide deliverypeptide-polymer conjugatespolymerizationscaled synthesis

Identifiers

PMID32659039
PMCPMC7722202
OpenAlexW3041785938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.