Evidence map›Paper›PMID 32659036›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Survival benefit of accepting kidneys from older donation after cardiac death donors.

Sile Yu, Jane J Long, Yifan Yu, Mary G Bowring, Jennifer D Motter, Tanveen Ishaque, Niraj Desai, Dorry L Segev, Jacqueline M Garonzik-Wang, Allan B Massie

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sile YuDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-9956-2526
Jane J LongDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Yifan YuDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Mary G BowringDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-7299-7730
Jennifer D MotterDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-1750-0119
Tanveen IshaqueDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-3523-243X
Niraj DesaiDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dorry L SegevDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-1924-4801
Jacqueline M Garonzik-WangDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Allan B MassieDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-5288-5125

Funding

Medical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4M
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
Determinants of chronic kidney disease in African-American live kidney donorsK01DK101677 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI MASSIE, ALLAN B · 2015 to 2019
$789k
Aggressive Center Report Cards to Safely Increase Transplantation of Suboptimal KidneysK23DK115908 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI GARONZIK WANG, JACQUELINE M · 2018 to 2021
$516k
NIDDK NIH HHS K01 DK101677NIDDK NIH HHS K01DK101677NIDDK NIH HHS K23 DK115908NIDDK NIH HHS K23DK115908NIDDK NIH HHS K24 DK101828NIDDK NIH HHS K24DK101828NIGMS NIH HHS T32 GM136577
6 · The paper itself

Abstract

Kidneys from older (age ≥50 years) donation after cardiac death (DCD50) donors are less likely to be transplanted due to inferior posttransplant outcomes. However, candidates who decline a DCD50 offer must wait for an uncertain future offer. To characterize the survival benefit of accepting DCD50 kidneys, we used 2010-2018 Scientific Registry for Transplant Recipients (SRTR) data to identify 92 081 adult kidney transplantation candidates who were offered a DCD50 kidney that was eventually accepted for transplantation. DCD50 kidneys offered to candidates increased from 590 in 2010 to 1441 in 2018. However, 34.6% of DCD50 kidneys were discarded. Candidates who accepted DCD50 offers had 49% decreased mortality risk (adjusted hazard ratio [aHR]

Indexed as

Tissue and Organ ProcurementAdultDeathDonor SelectionGraft SurvivalHumansKidneyMiddle AgedRegistriesTissue Donorsclinical decision-makingclinical research/practicedonors and donation: donation after circulatory death (DCD)epidemiologyhealth services and outcomes researchkidney transplantation/nephrologyorgan procurement and allocationpatient survivalScientific Registry for Transplant Recipients (SRTR)

Identifiers

PMID32659036
PMCPMC8547550

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.