Evidence map›Paper›PMID 32658934›Full record

ArticlePloS one2020

Voice quality and speech fluency distinguish individuals with Mild Cognitive Impairment from Healthy Controls.

Charalambos Themistocleous, Marie Eckerström, Dimitrios Kokkinakis

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 104 citations in OpenAlex.

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  9. Clinical validation of a voice-based AI tool for screening cognitive impairment: a prospective multicenter study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  13. Domain generalization for voice-based cognitive impairment detection.BMC medical informatics and decision making · 2025
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  15. Obfuscation via pitch-shifting for balancing privacy and diagnostic utility in voice-based cognitive assessment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Charalambos ThemistocleousDepartment of Neurology, Johns Hopkins University, Baltimore, Maryland, United States of America.ORCID 0000-0002-9138-0939
Marie EckerströmDepartment of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden.
Dimitrios KokkinakisDepartment of Swedish, University of Gothenburg, Gothenburg, Sweden.
University of Gothenburg · SEJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild Cognitive Impairment (MCI) is a syndrome characterized by cognitive decline greater than expected for an individual's age and education level. This study aims to determine whether voice quality and speech fluency distinguish patients with MCI from healthy individuals to improve diagnosis of patients with MCI. We analyzed recordings of the Cookie Theft picture description task produced by 26 patients with MCI and 29 healthy controls from Sweden and calculated measures of voice quality and speech fluency. The results show that patients with MCI differ significantly from HC with respect to acoustic aspects of voice quality, namely H1-A3, cepstral peak prominence, center of gravity, and shimmer; and speech fluency, namely articulation rate and averaged speaking time. The method proposed along with the obtainability of connected speech productions can enable quick and easy analysis of speech fluency and voice quality, providing accessible and objective diagnostic markers of patients with MCI.

Indexed as

AgedCase-Control StudiesCognitive DysfunctionDysphoniaFemaleHumansIncidenceMaleSpeechSwedenVoice Quality

Identifiers

PMID32658934
PMCPMC7357785
OpenAlexW3042015757

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.