Evidence map›Paper›PMID 32658589›Full record

ReviewExpert review of medical devices2020

Should we overcome the resistance to bioelectrical impedance in heart failure?

Stephen J Hankinson, Charles H Williams, Van-Khue Ton, Stephen S Gottlieb, Charles C Hong

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of medical devices, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Subclinical congestion assessed by whole-body bioelectrical impedance analysis in HFrEF outpatients.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025
    Article
  4. Observational
  5. Article
  6. New aspects in cardiorenal syndrome and HFpEF.Clinical kidney journal · 2022
    Review
  7. Article
  8. Cardiovascular Diseases Diagnosis by Impedance Cardiography.Journal of electrical bioimpedance · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stephen J HankinsonDepartment of Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine , Baltimore, MD, USA.
Charles H WilliamsDepartment of Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine , Baltimore, MD, USA.
Van-Khue TonDepartment of Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine , Baltimore, MD, USA.
Stephen S GottliebDepartment of Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine , Baltimore, MD, USA.
Charles C HongDepartment of Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine , Baltimore, MD, USA.
University of Maryland, Baltimore · USHarvard University · US

Funding

Regulation and Maintenance of Cardiac Muscle Sarcomere IntegrityR01HL095813 · NHLBI · VANDERBILT UNIVERSITY · PI HONG, CHARLES C · 2010 to 2014
$2.1M
Novel Approach to Enhance Myocardial Performance and Improve Heart Failure OutcomeR01HL135129 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HONG, CHARLES C · 2018 to 2021
$1.6M
NHLBI NIH HHS R01 HL095813NHLBI NIH HHS R01 HL135129
6 · The paper itself

Abstract

introductionHeart failure is associated with increased neurohormonal activation that results in changes in body composition including volume overload and the loss of skeletal muscle, body fat, and bone density. Bioelectrical impedance measures body composition based on the conduction of electrical current through body fluids. AREAS COVERED: The PubMed and Scopus databases were reviewed up to the third week of June 2020. Cross-sectional studies, retrospective observational studies, prospective observational studies, and randomized controlled trials have examined numerous bioelectrical impedance monitoring strategies to guide the diagnosis, prognosis, and treatment of heart failure. These monitoring strategies include intrathoracic impedance, lung impedance, bioelectrical impedance vector analysis, leg bioelectrical impedance, and thoracic bioreactance. EXPERT COMMENTARY: Based on the current evidence, more studies are needed to validate bioelectrical impedance in heart failure. Lung impedance appears to be useful for guiding heart failure treatment in patients with ST-elevation myocardial infarction and improving outcomes in outpatients with heart failure. Furthermore, bioelectrical impedance has potential as a noninvasive, quantitative heart failure variable for population-based research.

Indexed as

Electric ImpedanceBody CompositionHeart FailureHumansLegMonitoring, PhysiologicPrognosisBioelectrical impedancebioelectrical impedance vector analysisbioimpedancebioreactanceheart failureintrathoracic impedanceleg bioelectrical impedancelung impedance

Identifiers

PMID32658589
PMCPMC8356137
OpenAlexW3042369978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.