Evidence map›Paper›PMID 32658479›Full record

ArticleJournal of medicinal chemistry2020

Imaging Biotin Trafficking In Vivo with Positron Emission Tomography.

Salvatore Bongarzone, Teresa Sementa, Joel Dunn, Jayanta Bordoloi, Kavitha Sunassee, Philip J Blower, Antony Gee

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Biotin Homeostasis and Human Disorders: Recent Findings and Perspectives.International journal of molecular sciences · 2024
    Review
  8. Rapid, biochemical tagging of cellular activity history in vivo.bioRxiv : the preprint server for biology · 2024
    Article
  9. Review
  10. Review
  11. Review
  12. Diagnostic and Therapeutic Radiopharmaceuticals.ACS pharmacology & translational science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Salvatore BongarzoneSchool of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London SE1 7EH, United Kingdom.ORCID 0000-0002-1309-3045
Teresa SementaSchool of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London SE1 7EH, United Kingdom.
Joel DunnSchool of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London SE1 7EH, United Kingdom.
Jayanta BordoloiSchool of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London SE1 7EH, United Kingdom.
Kavitha SunasseeSchool of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London SE1 7EH, United Kingdom.
Philip J BlowerSchool of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London SE1 7EH, United Kingdom.
Antony GeeSchool of Biomedical Engineering & Imaging Sciences, St Thomas' Hospital, King's College London, London SE1 7EH, United Kingdom.ORCID 0000-0001-8389-9012
St Thomas' Hospital · GB

Funding

Medical Research Council MR/K022733/1Wellcome TrustWellcome Trust WT 203148/Z/16/Z
6 · The paper itself

Abstract

The water-soluble vitamin biotin is essential for cellular growth, development, and well-being, but its absorption, distribution, metabolism, and excretion are poorly understood. This paper describes the radiolabeling of biotin with the positron emission tomography (PET) radionuclide carbon-11 ([

Indexed as

Positron-Emission TomographyAnimalsBiotinCarbon RadioisotopesFemaleMaleMice, Inbred BALB CTissue DistributionVitamin B ComplexBiotinCarbon-11Carbon RadioisotopesVitamin B Complex

Identifiers

PMID32658479
PMCPMC7445742
OpenAlexW3042292221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.