Evidence map›Paper›PMID 32658309›Full record

ArticleDevelopmental psychobiology2021

Integrated and diurnal indices of maternal pregnancy cortisol in relation to sex-specific parasympathetic responsivity to stress in infants.

Whitney Cowell, Jennifer E Khoury, Carter R Petty, Helen E Day, Brian E Benítez, Molly K Cunningham, Stefan M Schulz, Thomas Ritz, Rosalind J Wright, Michelle Bosquet Enlow

Open access · greenAbstract read
In one paragraph

Article in Developmental psychobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Whitney CowellDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0002-1824-3356
Jennifer E KhouryDepartment of Psychiatry, Cambridge Hospital, Cambridge, MA, USA.
Carter R PettyInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, MA, USA.
Helen E DayDepartment of Psychiatry, Boston Children's Hospital, Boston, MA, USA.
Brian E BenítezDepartment of Psychiatry, Boston Children's Hospital, Boston, MA, USA.
Molly K CunninghamDepartment of Psychiatry, Boston Children's Hospital, Boston, MA, USA.
Stefan M SchulzClinical Psychology, Psychotherapy, and Experimental Psychopathology, Johannes Gutenberg University Mainz, Mainz, Germany.
Thomas RitzDepartment of Psychology, Southern Methodist University, Dallas, TX, USA.
Rosalind J WrightDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Michelle Bosquet EnlowDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Boston Children's Hospital · USHarvard University · USIcahn School of Medicine at Mount Sinai · USJohannes Gutenberg University Mainz · DEMount Sinai Hospital · USSouthern Methodist University · US

Funding

Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Chris Gennings · 2014 to 2026
$21.3M
Research Training Program in Pediatric ExposomicsT32HD049311 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2007 to 2026
$7.4M
Early life stress, telomere attrition, and child prefrontal cortex functioningR01HD082078 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI BOSQUET ENLOW, MICHELLE A · 2015 to 2020
$3.4M
Perinatal Programming of Infant Stress Reactivity and the Atopic PhenotypeR01HL095606 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI BOSQUET ENLOW, MICHELLE A, WRIGHT, ROSALIND J · 2010 to 2013
$3.1M
Prenatal stress and epigenetic programming of the HPA axis and autonomic balanceR01HL114396 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2012 to 2015
$2.8M
Advancing use of hair and salivary cortisol in stress-asthma researchR21HD080359 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WRIGHT, ROSALIND J · 2015 to 2016
$455k
NHLBI NIH HHS R01 HL095606NHLBI NIH HHS R01 HL114396NICHD NIH HHS R01 HD082078NICHD NIH HHS R21 HD080359NICHD NIH HHS T32 HD049311NIEHS NIH HHS P30 ES023515NIH HHS UH3 OD023337
6 · The paper itself

Abstract

Maternal hypothalamic-pituitary-adrenal axis activity may prenatally program sex-specific stress-response pathways. We investigated associations between maternal cortisol during pregnancy and infant parasympathetic responsivity to stress among 204 mother-infant pairs. Cortisol indices included 3rd trimester hair cortisol, as well as diurnal slope and area under the curve, derived from saliva samples collected during pregnancy. Mother-infant dyads participated in the Repeated Still-Face Paradigm (SFP-R) at age 6 months. We calculated respiration-adjusted respiratory sinus arrhythmia (RSA

Indexed as

HydrocortisonePrenatal Exposure Delayed EffectsFemaleHumansHypothalamo-Hypophyseal SystemInfantMaleMothersPituitary-Adrenal SystemPregnancySalivaStress, PsychologicalHydrocortisoneautonomiccortisolHPA axisparasympatheticprenatalstress response

Identifiers

PMID32658309
PMCPMC7855344
OpenAlexW3043735204

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.