Evidence map›Paper›PMID 32657758›Full record

ArticleeLife2020

Microtubules originate asymmetrically at the somatic golgi and are guided via Kinesin2 to maintain polarity within neurons.

Amrita Mukherjee, Paul S Brooks, Fred Bernard, Antoine Guichet, Paul T Conduit

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 54 citations in OpenAlex.

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  7. Asymmetry of centrosomes inMolecular biology of the cell · 2025
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  17. Live Imaging of Golgi Outposts in Drosophila Dendritic Arbors.Methods in molecular biology (Clifton, N.J.) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Amrita MukherjeeDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.
Paul S BrooksDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.
Fred BernardUniversité de Paris, CNRS, Institut Jacques Monod, Paris, France.ORCID 0000-0002-7919-253X
Antoine GuichetUniversité de Paris, CNRS, Institut Jacques Monod, Paris, France.ORCID 0000-0001-7216-1944
Paul T ConduitDepartment of Zoology, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-7822-1191
Centre National de la Recherche Scientifique · FRUniversity of Cambridge · GB

Funding

Association pour la Recherche sur le Cancer PJA 20181208148Isaac Newton Trust 18.23(p)Wellcome 105653/Z/14/ZWellcome Trust
6 · The paper itself

Abstract

Neurons contain polarised microtubule arrays essential for neuronal function. How microtubule nucleation and polarity are regulated within neurons remains unclear. We show that γ-tubulin localises asymmetrically to the somatic Golgi within

Indexed as

AnimalsCell PolarityDrosophila melanogasterDrosophila ProteinsGolgi ApparatusKinesinsLarvaMicrotubulesNeuronsDrosophila Proteinskinesin 2 protein, DrosophilaKinesinscell biologyD. melanogasterGolgig-turcKinesin-2microtubulesneuronsneurosciencepolarity

Identifiers

PMID32657758
PMCPMC7394546
OpenAlexW3042466378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.