Evidence map›Paper›PMID 32657334›Full record

ArticleAmerican journal of hypertension2020

Using Predicted Atherosclerotic Cardiovascular Disease Risk for Discrimination of Awake or Nocturnal Hypertension.

Swati Sakhuja, John N Booth, David E Anstey, Byron C Jaeger, Cora E Lewis, Donald M Lloyd-Jones, Joseph E Schwartz, Daichi Shimbo, James M Shikany, Mario Sims and 1 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of hypertension, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Swati SakhujaDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
John N BoothDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
David E AnsteyDepartment of Medicine, Columbia University, New York, New York, USA.
Byron C JaegerDepartment of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Cora E LewisDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Donald M Lloyd-JonesDepartment of Preventive Medicine, Northwestern University, Chicago, Illinois, USA.
Joseph E SchwartzDepartment of Medicine, Columbia University, New York, New York, USA.
Daichi ShimboDepartment of Medicine, Columbia University, New York, New York, USA.
James M ShikanyDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Mario SimsDepartment of Medicine, University of Mississippi, Jackson, Mississippi, USA.
Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
University of Alabama at Birmingham · USColumbia University · USNorthwestern University · USStony Brook University · USUniversity of Mississippi · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI W Timothy GARVEY · 2013 to 2026
$19.5M
Incorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2M
Psychological stress, and circadian patterns of sodium excretion and blood pressureR01HL137818 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2018 to 2021
$2.4M
Midcareer Investigator Award in Patient-Oriented Research in Human HypertensionK24HL125704 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2015 to 2019
$573k
NHLBI NIH HHS HHSN268201800003INHLBI NIH HHS HHSN268201800004INHLBI NIH HHS HHSN268201800005INHLBI NIH HHS HHSN268201800006INHLBI NIH HHS HHSN268201800007INHLBI NIH HHS HHSN268201800010INHLBI NIH HHS HHSN268201800011CNHLBI NIH HHS HHSN268201800011INHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014CNHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INHLBI NIH HHS K24 HL125704NHLBI NIH HHS R01 HL117323NHLBI NIH HHS R01 HL137818NIDDK NIH HHS P30 DK079626NIMHD NIH HHS HHSN268201800013I
6 · The paper itself

Abstract

backgroundSeveral atherosclerotic cardiovascular disease (ASCVD) risk factors are associated with awake and nocturnal hypertension.

methodsWe assessed the association between a composite ASCVD risk score and awake or nocturnal hypertension using data from participants aged 40-79 years who completed ambulatory blood pressure monitoring at the Year 30 Coronary Artery Risk Development in Young Adults study exam in 2015-2016 (n = 716) and the baseline Jackson Heart Study exam in 2000-2004 (n = 770). Ten-year predicted ASCVD risk was calculated using the Pooled Cohort risk equations. Awake hypertension was defined as mean awake systolic blood pressure (SBP) ≥135 mm Hg or diastolic blood pressure (DBP) ≥85 mm Hg and nocturnal hypertension was defined as mean asleep SBP ≥120 mm Hg or DBP ≥70 mm Hg.

resultsAmong participants with a 10-year predicted ASCVD risk <5%, 5% to <7.5%, 7.5% to <10%, and ≥10%, the prevalence of awake or nocturnal hypertension as a composite outcome was 29.5%, 47.8%, 62.2%, and 69.7%, respectively. After multivariable adjustment, higher ASCVD risk was associated with higher prevalence ratios for awake or nocturnal hypertension among participants with clinic-measured SBP/DBP <130/85 mm Hg but not ≥130/85 mm Hg. The C-statistic for discriminating between participants with vs. without awake or nocturnal hypertension was 0.012 (95% confidence interval 0.003, 0.016) higher when comparing a model with ASCVD risk and clinic-measured blood pressure (BP) together vs. clinic-measured BP without ASCVD risk.

conclusionsUsing 10-year predicted ASCVD risk in conjunction with clinic BP improves discrimination between individuals with and without awake or nocturnal hypertension.

Indexed as

ArteriosclerosisBlood Pressure Monitoring, AmbulatoryCircadian RhythmHypertensionRisk AssessmentBlood PressureCross-Sectional StudiesFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedPrevalencePrognosisUnited Statesatherosclerotic cardiovascular disease riskawake hypertensionblood pressurehypertensionnocturnal hypertensionPooled Cohort risk equations

Identifiers

PMID32657334
PMCPMC7608525
OpenAlexW3042278595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.