Evidence map›Paper›PMID 32657271›Full record

ArticleeLife2020

Growth cone-localized microtubule organizing center establishes microtubule orientation in dendrites.

Xing Liang, Marcela Kokes, Richard D Fetter, Maria Danielle Sallee, Adrian W Moore, Jessica L Feldman, Kang Shen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 63 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xing Liang *Department of Biology, Stanford University, Stanford, United States.ORCID 0000-0002-8298-1214
Marcela Kokes *Department of Biology, Stanford University, Stanford, United States.ORCID 0000-0002-7218-481X
Richard D FetterHoward Hughes Medical Institute, Stanford University, Stanford, United States.ORCID 0000-0002-1558-100X
Maria Danielle SalleeDepartment of Biology, Stanford University, Stanford, United States.
Adrian W MooreRIKEN Center for Brain Science, Wako, Japan.
Jessica L FeldmanDepartment of Biology, Stanford University, Stanford, United States.ORCID 0000-0002-5210-5045
Kang ShenDepartment of Biology, Stanford University, Stanford, United States.ORCID 0000-0003-4059-8249
Howard Hughes Medical Institute · USStanford University · USRIKEN Center for Brain Science · JP

Funding

Stanford Training Program in Aging ResearchT32AG047126 · NIA · STANFORD UNIVERSITY · PI VYJEYANTHI S PERIYAKOIL, TONY WYSS-CORAY · 2014 to 2026
$4.3M
Patterning dendritic branches with environmental and neuronal surface moleculesR01NS082208 · NINDS · STANFORD UNIVERSITY · PI KANG SHEN · 2013 to 2026
$4.1M
Mechanisms controlling microtubule organization during cell differentiationDP2GM119136 · NIGMS · STANFORD UNIVERSITY · PI FELDMAN, JESSICA LYNN · 2015 to 2015
$2.4M
Investigating the establishment, structure, and function of microtubule organizing centers in differentiated cells in vivoR01GM133950 · NIGMS · STANFORD UNIVERSITY · PI FELDMAN, JESSICA LYNN · 2020 to 2023
$1.3M
Remodeling the microtubule cytoskeleton during epithelial cell division and differentiationK99GM135489 · NIGMS · STANFORD UNIVERSITY · PI SALLEE, MARIA DANIELLE · 2020 to 2022
$284k
Regulating the Coordination of Microtubule Organization and Cell Cycle StateF32GM120913 · NIGMS · STANFORD UNIVERSITY · PI SALLEE, MARIA DANIELLE · 2016 to 2018
$116k
NIA NIH HHS T32 AG047126NIGMS NIH HHS DP2 GM119136NIGMS NIH HHS F32 GM120913NIGMS NIH HHS K99 GM135489NIGMS NIH HHS R01 GM133950NINDS NIH HHS R01 NS082208
6 · The paper itself

Abstract

A polarized arrangement of neuronal microtubule arrays is the foundation of membrane trafficking and subcellular compartmentalization. Conserved among both invertebrates and vertebrates, axons contain exclusively 'plus-end-out' microtubules while dendrites contain a high percentage of 'minus-end-out' microtubules, the origins of which have been a mystery. Here we show that in

Indexed as

AnimalsCaenorhabditis elegansDendritesGrowth ConesMicrotubule-Organizing CenterMicrotubulesacentrosomal mtocC. eleganscell biologydendrite developmentdevelopmental biologymicrotubule organizationneuronal cell polarityγ-TuRC

Identifiers

PMID32657271
PMCPMC7375809
OpenAlexW2985168002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.