ArticleEpigenetics
Mitochondrial DNA methylation in placental tissue: a proof of concept study by means of prenatal environmental stressors.
Article in Epigenetics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: An update of a systematic literature review.Mutation research. Reviews in mutation researchPooled it
- Air pollution and adverse birth outcomes: a narrative review of epidemiological and mechanistic findings.Journal of environmental health science & engineering · 2026Review
- Mitochondrial D-Loop Region Methylation Is Not Altered in Children with Autism Spectrum Disorder.Epigenomes · 2026Article
- Epigenetic reprogramming by air pollution: linking prenatal exposures to birth outcomes.Molecular and cellular biochemistry · 2025Review
- Environmental Pollution and Reproductive Health: The Cause for Concern.Journal of obstetrics and gynaecology of India · 2025Review
- Reduction in mitochondrial DNA methylation leads to compensatory increase in mitochondrial DNA content: novel blood-borne biomarkers for monitoring occupational noise.Environmental health and preventive medicine · 2025Article
- Mitochondrial DNA content and methylation in sperm of patients with asthenozoospermia.Journal of assisted reproduction and genetics · 2024Article
- Ambient air pollution and adverse birth outcomes: A review of underlying mechanisms.BJOG : an international journal of obstetrics and gynaecology · 2024Review
- Maternal mitochondrial DNA copy number and methylation as possible predictors of pregnancy outcomes in a Michigan pregnancy cohort.Environmental epigenetics · 2024Article
- Characterization of Mitochondrial DNA Methylation of Alzheimer's Disease in Plasma Cell-Free DNA.Diagnostics (Basel, Switzerland) · 2023Article
- The prenatal environment and its influence on maternal and child mitochondrial DNA copy number and methylation: A review of the literature.Environmental research · 2023Review
- Article
- Select Early-Life Environmental Exposures and DNA Methylation in the Placenta.Current environmental health reports · 2023Review
- Mitochondrial DNA methylation in metabolic associated fatty liver disease.Frontiers in nutrition · 2023Article
- Lupus, DNA Methylation, and Air Pollution: A Malicious Triad.International journal of environmental research and public health · 2022Review
- Epigenetics and Pregnancy: Conditional Snapshot or Rolling Event.International journal of molecular sciences · 2022Review
- Mitochondrial changes in fish cells in vitro in response to serum deprivation.Fish physiology and biochemistry · 2022Article
- Mitochondrial DNA and Epigenetics: Investigating Interactions with the One-Carbon Metabolism in Obesity.Oxidative medicine and cellular longevity · 2022Article
- Single-molecule mitochondrial DNA sequencing shows no evidence of CpG methylation in human cells and tissues.Nucleic acids research · 2021Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While previous studies have demonstrated that prenatal exposure to environmental stressors is associated with mitochondrial DNA (mtDNA) methylation, more recent investigations are questioning the accuracy of the methylation assessment and its biological relevance. In this study, we investigated placental mtDNA methylation while accounting for methodological issues such as nuclear contamination, bisulphite conversion, and PCR bias. From the ENVIR
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.