Evidence map›Paper›PMID 32657019›Full record

ArticleEMBO reports2020

Hypothalamic CDK4 regulates thermogenesis by modulating sympathetic innervation of adipose tissues.

Judit Castillo-Armengol, Valentin Barquissau, Sarah Geller, Honglei Ji, Ilenia Severi, Wiebe Venema, Eric Aria Fenandez, Catherine Moret, Katharina Huber, Lucia C Leal-Esteban and 11 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EMBO reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. International journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Hypothalamic control of energy expenditure and thermogenesis.Experimental & molecular medicine · 2022
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 3 countries.

Judit Castillo-ArmengolCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0001-7833-0569
Valentin BarquissauCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Sarah GellerCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Honglei JiCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Ilenia SeveriDepartment of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy.
Wiebe VenemaDepartment of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy.
Eric Aria FenandezCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Catherine MoretCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Katharina HuberCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Lucia C Leal-EstebanCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Anita NasrallahCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Laia Martinez-CarreresCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Guy NiederhäuserCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Patricia Seoane-CollazoNeurObesity Group, Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.
Sylviane LagarrigueDepartment of Physiology, University of Lausanne, Lausanne, Switzerland.
Miguel LópezNeurObesity Group, Department of Physiology, CIMUS, University of Santiago de Compostela-Instituto de Investigación Sanitaria, Santiago de Compostela, Spain.ORCID 0000-0002-7823-1648
Antonio GiordanoDepartment of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy.
Sophie CroizierCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-0076-1008
Bernard ThorensCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Isabel C Lopez-MejiaCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.
Lluis FajasCenter for Integrative Genomics, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0002-1283-9503
University of Lausanne · CHMarche Polytechnic University · ITUniversidade de Santiago de Compostela · ES

Funding

Ministerio de Ciencia, Innovación y Universidades (Ministry of Science, Innovation and Universities) ML: RTI2018-101840-B-I00Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 31003A_143369Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) PZ00P3_168077
6 · The paper itself

Abstract

This study investigated the role of CDK4 in the oxidative metabolism of brown adipose tissue (BAT). BAT from Cdk4

Indexed as

Adipose Tissue, WhiteThermogenesisAdipocytes, BrownAdipose Tissue, BrownAnimalsHypothalamusMiceadrenergic innervationbrown adipose tissueCDK4hypothalamusmitochondriathermogenesis

Identifiers

PMID32657019
PMCPMC7507572
OpenAlexW3041552554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.