Evidence map›Paper›PMID 32656670›Full record

ArticleWorld journal of urology2021

Achieving the "trifecta" with open versus minimally invasive partial nephrectomy.

Samrad Ghavimi, Olli Saarela, Frederic Pouliot, Ricardo A Rendon, Antonio Finelli, Anil Kapoor, Ronald B Moore, Rodney H Breau, Luke Lavallee, Louis Lacombe and 5 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Samrad GhavimiUniversity of British Columbia, Level 6, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada.
Olli SaarelaUniversity of Toronto, 610 University Avenue Toronto, Toronto, ON, M5G 2M9, Canada.
Frederic PouliotL'Hôtel-Dieu de Québec, 6 rue McMahon 0624, Quebec City, QC, G1R 2J6, Canada.
Ricardo A RendonDalhousie University, VG Site-5th Floor Centennial Room 5015, 1276 South Park Street, Halifax, NS, B3H 2Y9, Canada.
Antonio FinelliUniversity of Toronto, 610 University Avenue Toronto, Toronto, ON, M5G 2M9, Canada.
Anil KapoorMcMaster University, 50 Charlton Ave E, Room G344, Hamilton, ON, L8N 4A6, Canada.
Ronald B MooreKaye Edmonton Clinic, University of Alberta, 11400 University Avenue, 7th Floor, Edmonton, AB, T6G 1Z1, Canada.
Rodney H BreauUniversity of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
Luke LavalleeUniversity of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada.
Louis LacombeL'Hôtel-Dieu de Québec, 6 rue McMahon 0624, Quebec City, QC, G1R 2J6, Canada.
Adrian FaireyKaye Edmonton Clinic, University of Alberta, 11400 University Avenue, 7th Floor, Edmonton, AB, T6G 1Z1, Canada.
Michael JewettUniversity of Toronto, 610 University Avenue Toronto, Toronto, ON, M5G 2M9, Canada.
Zhihui LiuUniversity of Toronto, 610 University Avenue Toronto, Toronto, ON, M5G 2M9, Canada.
Simon TanguayMcGill University, 1650 Cedar Avenue, Montreal, QC, H3G 1A4, Canada.
Peter C BlackUniversity of British Columbia, Level 6, 2775 Laurel Street, Vancouver, BC, V5Z 1M9, Canada. pblack@mail.ubc.ca.ORCID http://orcid.org/0000-0002-2919-7068
University of Toronto · CAHôtel-Dieu de Québec · CAUniversity of Alberta · CAUniversity of British Columbia · CAUniversity of Ottawa · CADalhousie University · CAMcGill University · CAMcMaster University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe "trifecta" is a summary measure of outcome after partial nephrectomy (PN) that encompasses three parameters: negative surgical margin, ≤ 10% decrease in post-operative estimated glomerular filtration rate (eGFR) and absence of urological complications. We assessed trifecta rates in patients undergoing open (OPN), laparoscopic (LPN), and robotic PN (RPN) for a clinical T1 renal mass (≤ 7 cm).

methodsClinical and pathologic parameters were extracted from the prospectively maintained Canadian Kidney Cancer Information System for patients treated between January 2011 and October 2018. Comparisons between groups were made using Kruskal-Wallis test for continuous variables and Chi-squared independence test for categorical variables. Multivariable analysis was performed to identify predictors of each component of the trifecta and the trifecta itself.

resultsOf 1708 total patients, 746 underwent OPN, 678 LPN, and 284 RPN for a T1 renal mass. A 'trifecta' was achieved in 53% OPN, 52% LPN and 47% RPN (p = 0.194). On multivariable analysis, OPN and LPN were associated with less frequent post-operative decline in eGFR and more frequent trifecta when compared to RPN, but there was no difference between OPN and LPN. OPN also predicted a higher rate of negative margins compared to RPN but not LPN.

conclusionAfter correction for confounding variables, OPN and LPN were more likely than RPN to achieve the trifecta, which appeared to be due primarily to loss of renal function. No difference was observed between OPN and LPN. Analyses were limited by the lack of nephrometry score.

Indexed as

LaparoscopyRobotic Surgical ProceduresAgedFemaleGlomerular Filtration RateHumansKidney NeoplasmsMaleMargins of ExcisionMiddle AgedNephrectomyPostoperative ComplicationsProspective StudiesTreatment OutcomeMinimally invasive versus openPartial nephrectomyTrifecta

Identifiers

PMID32656670
OpenAlexW3041497665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.