SynthesisWorld journal of surgery2020
Prehabilitation in Frail Surgical Patients: A Systematic Review.
Synthesis in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 5 syntheses or guidelines pooled it, 92 citations in OpenAlex.
- The influence of frailty on outcomes of adult spinal deformity surgery: A systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Effect of Prehabilitation on the 6-Minute Walk Test and Length of Hospital Stay in Frail Older People: A Meta-Analysis of Randomized Controlled Trials.International journal of environmental research and public health · 2025Pooled it
- Comparative Analysis of Open, Laparoscopic, and Robotic Pancreaticoduodenectomy: A Systematic Review of Randomized Controlled Trials.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Frailty indices in patients undergoing surgical resection of brain metastases: a systematic review.Neurosurgical review · 2023Pooled it
- Effects of prehabilitation on postoperative outcomes in frail cancer patients undergoing elective surgery: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Facilitators and barriers to participation in prehabilitation prior to orthopaedic elective surgery - a qualitative study with elderly (pre-)frail patients.BMC geriatrics · 2025Trial
- Barriers and facilitators to participation in exercise prehabilitation before cancer surgery for older adults with frailty: a qualitative study.BMC geriatrics · 2023Trial
- Trial
- The frailty mortality link in people with chronic diseases pertaining to 13 body organ systems: findings from the UK Biobank study.GeroScience · 2026Article
- Superior predictive performance of the Risk Analysis Index over the modified Frailty Index-5 in patients undergoing elective anterior cervical procedures among octogenarians.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Effects of Oral Frailty Index-8 Score on Complications After Major Orthopaedic Surgery: A Single-Center Retrospective Study.Journal of oral rehabilitation · 2026Article
- Frailty and social support in older orthopedic surgical patients: a cross-sectional analysis.BMC geriatrics · 2026Article
- Preoperative prehabilitation in adults: A concept analysis.International journal of nursing studies advances · 2026Review
- Postoperative outcomes in patients with gastric cancer undergoing prehabilitation in a high-complexity referral centre.World journal of surgical oncology · 2026Observational
- The Association Between Inflammatory Scores and Frailty Severity: An Exploratory Retrospective Analysis in Non-Small-Cell Lung Cancer Surgical Patients.Medical sciences (Basel, Switzerland) · 2026Article
- Integrating Pain Prehabilitation into Surgical Pathways: Current Modalities, Outcomes, and Research Gaps.Current pain and headache reports · 2026Review
- Impact of Preoperative Comprehensive Body Composition on Postoperative Outcomes in Patients with Esophageal Cancer.Journal of clinical medicine · 2025Article
- Integrating Prehabilitation into Surgical Pathways: Current Modalities, Outcomes, and Research Gaps.medRxiv : the preprint server for health sciences · 2025Article
- Differential impact of frailty on surgical and non-surgical site complications in patients with gastric cancer undergoing gastrectomy.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025Article
- Pre-operative education and prehabilitation provision for patients undergoing hip and knee replacement: a national survey of current NHS practice.BMC musculoskeletal disorders · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty is a customized marker of biological age that helps to gauge an individual's functional physiologic reserve and ability to react to stress and is associated with increased postoperative morbidity and mortality. In order to mitigate frailty preoperatively, the concept of prehabilitation has entered the forefront which encompasses multidisciplinary interventions to improve health and lessen the incidence of postoperative decline. The purpose of this study is to investigate the impact of prehabilitation on postoperative outcomes in frail, surgical patients.
methodsA comprehensive literature search was performed by two independent researchers according to PRISMA guidelines. Inclusion criteria were (1) a randomized controlled trial, case-control or observational study; (2) prehabilitation intervention; (3) frailty assessment; and (4) surgical intervention.
resultsThere were five articles included in the review. Evaluation of these articles demonstrated prehabilitation may improve operative outcomes in frail surgical patients. There were no assessments as to whether prehabilitation was cost-effective although it was feasible. Prehabilitation programs should include elements of exercise, nutrition, and psychosocial counseling. Frailty should be assessed with a validated index in surgical patients who may undergo prehabilitation.
conclusionPrehabilitation in frail surgical patients may be the appropriate process through which providers can lessen operative risk. Currently, however, there is little evidence supporting the use of prehabilitation in this population with only five studies identified in this systematic review. More randomized controlled trials are clearly needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.