Evidence map›Paper›PMID 32656206›Full record

ArticleFrontiers in cell and developmental biology2020

Contractility of Induced Pluripotent Stem Cell-Cardiomyocytes With an

Min-Su Kim, Brandon Fleres, Jerrell Lovett, Melissa Anfinson, Sai Suma K Samudrala, Lauren J Kelly, Laura E Teigen, Matthew Cavanaugh, Maribel Marquez, Aron M Geurts and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  8. Genes · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. International journal of molecular sciences · 2023
    Article
  15. Article
  16. Altered contractility, CaAmerican journal of physiology. Heart and circulatory physiology · 2023
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Min-Su KimDivision of Pediatric Cardiothoracic Surgery, Department of Surgery, Medical College of Wisconsin, Herma Heart Institute, Milwaukee, WI, United States.
Brandon FleresDepartment of Biological Sciences, Marquette University, Milwaukee, WI, United States.
Jerrell LovettDepartment of Biological Sciences, Marquette University, Milwaukee, WI, United States.
Melissa AnfinsonDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, United States.
Sai Suma K SamudralaDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, United States.
Lauren J KellyDepartment of Biological Sciences, Marquette University, Milwaukee, WI, United States.
Laura E TeigenDepartment of Biological Sciences, Marquette University, Milwaukee, WI, United States.
Matthew CavanaughDepartment of Biological Sciences, Marquette University, Milwaukee, WI, United States.
Maribel MarquezDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States.
Aron M GeurtsDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States.
John W LoughDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, United States.
Michael E MitchellDivision of Pediatric Cardiothoracic Surgery, Department of Surgery, Medical College of Wisconsin, Herma Heart Institute, Milwaukee, WI, United States.
Robert H FittsDepartment of Biological Sciences, Marquette University, Milwaukee, WI, United States.
Aoy Tomita-MitchellDivision of Pediatric Cardiothoracic Surgery, Department of Surgery, Medical College of Wisconsin, Herma Heart Institute, Milwaukee, WI, United States.
Medical College of Wisconsin · USMarquette University · US

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
INTEGRATED PHYSIOLOGY TRAINING--MOLECULE TO ORGANISMT32HL007852 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Matthew Robert Hodges · 1996 to 2026
$6.5M
Medical Scientist Training ProgramT32GM080202 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI BARBIERI, JOSEPH T, SALZMAN, NITA H · 2010 to 2024
$5.7M
NCATS NIH HHS UL1 TR001436NHLBI NIH HHS T32 HL007852NIGMS NIH HHS T32 GM080202
6 · The paper itself

Abstract

Hypoplastic left heart syndrome (HLHS) is a clinically and anatomically severe form of congenital heart disease; however, its etiology remains largely unknown. We previously demonstrated that genetic variants in the

Indexed as

contractilityCRISPR/Cas9HLHShypoplastic left heart syndromeiPSC-cardiomyocytesMYH6sarcomere

Identifiers

PMID32656206
PMCPMC7324479
OpenAlexW3034163767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.