ArticlePeerJ2020
Comparative metabolomic analyses of
Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Metabolomic Profiling Reveals Geographical Origin, Tissue-Specific Specialization, and Environmental Plasticity in Secondary Metabolism ofMetabolites · 2026Article
- Mechanisms of acclimation regulation and stress response to UV-B inFrontiers in plant science · 2026Article
- Uncovering the Molecular Response of Oregano (Current issues in molecular biology · 2025Article
- Comparative metabolomic analysis provides insights into the metabolite profiles of wild and cultivated Dendrobium flexicaule.BMC plant biology · 2025Article
- Metabolomic Analysis ofMolecules (Basel, Switzerland) · 2024Article
- UV-B Radiation EnhancesPlants (Basel, Switzerland) · 2024Article
- Metabolic Pathway Engineering Improves Dendrobine Production inInternational journal of molecular sciences · 2023Article
- Potential Role of Phytochromes A and B and Cryptochrome 1 in the Adaptation ofInternational journal of molecular sciences · 2023Article
- Flavonoids metabolism and physiological response to ultraviolet treatments inFrontiers in plant science · 2022Article
- Quantitative Identification of Antioxidant Basis for Dendrobium Nobile Flower by High Performance Liquid Chromatography-Tandem Mass Spectrometry.International journal of analytical chemistry · 2022Article
- Phosphoproteomics Reveals Regulation of Secondary Metabolites inFrontiers in plant science · 2021Article
- Research Advances in Multi-Omics on the Traditional Chinese HerbFrontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background
methodsAn untargeted metabolomics method was used to investigate the metabolic variations in
resultsIn total, 3,655 annotated metabolites, including 640 up- and 783 down-regulated metabolites, were identified and grouped into various primary metabolic categories. Then, a number of metabolites involved in the polysaccharide, alkaloid and flavonoid biosynthesis pathways were identified. For polysaccharide biosynthesis, several intermediate products, such as pyruvate, secologanate, tryptophan and secologanin, were significantly up-regulated by the UV-B treatment. For polysaccharide biosynthesis, many key fundamental building blocks, from the glycolysis, starch and sucrose metabolism, and fructose and mannose metabolism pathways, were induced by the UV-B treatment. For flavonoid metabolism, accumulations of several intermediate products of chalcone synthase, chalcone isomerase and flavanone 3-hydroxylase were affected by the UV-B treatment, indicating an involvement of UV-B in flavonoid biosynthesis. The UV-B induced accumulation of polysaccharides, alkaloids and flavonoids was confirmed by HPLC analysis. Our study will help to understand the effects of UV-B on the accumulation of active ingredients in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.