Evidence map›Paper›PMID 32655841›Full record

ArticleOncotarget2020

Renal cell tumors convert natural killer cells to a proangiogenic phenotype.

Yue Guan, Christopher B Chambers, Taylor Tabatabai, Ha Hatley, Kristin R Delfino, Kathy Robinson, Shaheen R Alanee, Sophia Ran, Donald S Torry, Andrew Wilber

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. NK cells in renal cell carcinoma and its implications for CAR-NK therapy.Frontiers in cell and developmental biology · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Role of NK Cells in Tumor Progression.Experientia supplementum (2012) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yue GuanDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Christopher B ChambersDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Taylor TabatabaiDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Ha HatleyDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Kristin R DelfinoCenter for Clinical Research, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Kathy RobinsonDepartment of Internal Medicine, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Shaheen R AlaneeDepartment of Surgery, Division of Urology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Sophia RanDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Donald S TorryDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Andrew WilberDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA.
Southern Illinois University School of Medicine · USCenter for Clinical Research (United States) · US

Funding

Novel role of myeloid-derived lymphatic progenitors in induction of breast cancer lymphaticsR01CA199649 · NCI · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI RAN, SOPHIA · 2016 to 2020
$1.7M
FACS Aria II for Flow Cytometry Core FacilityS10RR025674 · NCRR · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI LIBERATI, TERESA · 2010 to 2010
$473k
Pro-inflammatory regulation of angiogenic gene expression in human trophoblastR15HD073868 · NICHD · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI TORRY, DONALD S. · 2012 to 2012
$437k
Renal Cell Tumor-Mediated Trans-differentiation of Natural Killer CellsR15CA173657 · NCI · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI WILBER, ANDREW CHRISTROPHER · 2013 to 2013
$375k
NCI NIH HHS R01 CA199649NCI NIH HHS R15 CA173657NCRR NIH HHS S10 RR025674NICHD NIH HHS R15 HD073868
6 · The paper itself

Abstract

Natural killer (NK) cells are classically associated with immune surveillance and destruction of tumor cells. Inconsistent with this function, NK cells are found in advanced human tumors including renal cell carcinoma (RCC). NK cells with non-classical phenotypes (CD56

Indexed as

angiogenesisimmunosuppressioninnate immunitykidney cancernatural killer cells

Identifiers

PMID32655841
PMCPMC7335666
OpenAlexW3039530932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.