ArticleAmerican journal of translational research2020
Carrying epirubicin on nanoemulsion containing algae and cinnamon oils augments its apoptotic and anti-invasion effects on human colon cancer cells.
Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Pomegranate Oil Nanoemulsion as a Nanotherapeutic Strategy Against Breast and Colon Cancer: Induction of Apoptosis and Inhibition of Cell Migration.Anti-cancer agents in medicinal chemistry · 2026Article
- Fabrication of α-lactalbumin-coated chamomile nano-emulsion for their synergistic anticancer and anti-inflammatory applications.Medical oncology (Northwood, London, England) · 2025Article
- γCyclodextrin-assisted Aqueous Extract of Cinnamon for Cancer and Stress Management.Current topics in medicinal chemistry · 2025Article
- Nanoemulsions in Skin Cancer Therapy: A Promising Frontier.Current pharmaceutical biotechnology · 2025Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nanotherapeutics holds great potential in cancer therapy since they may consist of more than one anticancer agent that has a different mechanism of action. The present study aimed to incorporate the epirubicin (EPI) into a nanoemulsion containing the algae and cinnamon oils (ALG-CN-EPI) using ultrasonication technique. The apoptotic efficacy of ALG-CN-EPI was assessed in the HCT116 human colon cancer cells using the assays of CCK-8, DNA fragmentation, reactive oxygen species (ROS) generation, and Annexin V-FITC/PI while the anti-invasion effect of ALG-CN-EPI was determined by the transwell invasion assay. The zeta average diameters and zeta potential of the nano-suspensions of ALG-CN-EPI, measured by the zetasizer, were 117.2 ± 3.02 nm and -1.810 ± 0.07 mV, respectively. Results of the apoptotic evaluation revealed that the half-maximal inhibitory concentration (IC
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Identifiers
32655784PMC7344066W3043299193What OpenQuestion holds
Registered trials
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