ArticleOxidative medicine and cellular longevity2020
Role of Gender and Physical Activity Level on Cardiovascular Risk Factors and Biomarkers of Oxidative Stress in the Elderly.
Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Fear of Falling Avoidance Behavior on Daily Living Activities and Physical Activity in Older Adults: A Cross-Sectional Study.Nursing & health sciences · 2025Article
- Men's more frequent predisposing factors in infectious endocarditis facilitate improvement of outcomes by shortening of diagnostic delay.Frontiers in cardiovascular medicine · 2024Article
- Sex-related differences in endothelial function and blood viscosity in the elderly population.Frontiers in physiology · 2023Article
- The Impact of Exercise on Redox Equilibrium in Cardiovascular Diseases.Journal of clinical medicine · 2022Review
- Level of advanced oxidation protein products is associated with subclinical atherosclerosis.BMC cardiovascular disorders · 2022Article
- Cardiovascular risk and aging: the need for a more comprehensive understanding.Journal of geriatric cardiology : JGC · 2021Article
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCardiovascular diseases remain as the leading cause of morbidity and mortality in industrialized countries. Ageing and gender strongly modulate the risk to develop cardiovascular diseases but very few studies have investigated the impact of gender on cardiovascular diseases in the elderly, which represents a growing population. The purpose of this study was to test the impact of gender and physical activity level on several biochemical and clinical markers of cardiovascular risk in elderly individuals.
methodsElderly individuals (318 women (75.8 ± 1.2 years-old) and 227 men (75.8 ± 1.1 years-old)) were recruited. Physical activity was measured by a questionnaire. Metabolic syndrome was defined using the National Cholesterol Education Program Expert Panel's definition. Polysomnography and digital tonometry were used to detect obstructive sleep apnea and assess vascular reactivity, respectively. Blood was sampled to measure several oxidative stress markers and adhesion molecules.
resultsThe frequency of cardiovascular diseases was significantly higher in men (16.4%) than in women (6.1%) (
conclusionThese findings suggest that biochemical cardiovascular risk factors are lower in women than men which could explain the lower cardiovascular disease proportion observed in women in the elderly.
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