Evidence map›Paper›PMID 32655720›Full record

ArticleDisease markers2020

Long Noncoding RNAs CARMN, LUCAT1, SMILR, and MALAT1 in Thoracic Aortic Aneurysm: Validation of Biomarkers in Clinical Samples.

Vaiva Patamsytė, Giedrius Žukovas, Dovydas Gečys, Diana Žaliaduonytė, Povilas Jakuška, Rimantas Benetis, Vaiva Lesauskaitė

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Post-transcriptional regulation of tumor suppressor gene lncRNA CARMN via mJournal of cancer research and clinical oncology · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Non-Coding RNAs as Blood-Based Biomarkers in Cardiovascular Disease.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Vaiva PatamsytėInstitute of Cardiology, Lithuanian University of Health Sciences, Sukilėlių pr. 15, Kaunas LT-50103, Lithuania.ORCID https://orcid.org/0000-0002-2270-1276
Giedrius ŽukovasDepartment of Cardiac, Thoracic and Vascular Surgery, Lithuanian University of Health Sciences, Eivenių g. 2, Kaunas LT-50161, Lithuania.
Dovydas GečysInstitute of Cardiology, Lithuanian University of Health Sciences, Sukilėlių pr. 15, Kaunas LT-50103, Lithuania.
Diana ŽaliaduonytėDepartment of Cardiology, Lithuanian University of Health Sciences, Eivenių g. 2, Kaunas LT-50161, Lithuania.
Povilas JakuškaDepartment of Cardiac, Thoracic and Vascular Surgery, Lithuanian University of Health Sciences, Eivenių g. 2, Kaunas LT-50161, Lithuania.
Rimantas BenetisInstitute of Cardiology, Lithuanian University of Health Sciences, Sukilėlių pr. 15, Kaunas LT-50103, Lithuania.
Vaiva LesauskaitėInstitute of Cardiology, Lithuanian University of Health Sciences, Sukilėlių pr. 15, Kaunas LT-50103, Lithuania.ORCID https://orcid.org/0000-0001-5674-2490
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MATERIALS AND

methodsRelative expression of lncRNAs CARMN, LUCAT1, SMILR, and MALAT1 was tested in clinical aortic tissue and blood plasma samples from TAA and non-TAA patients using the qRT-PCR method. The Mann-Whitney

resultsWe found significantly reduced CARMN (

conclusionsWe have shown that the expression of lncRNAs CARMN and LUCAT1 is reduced in dilated aortic tissue and that the LUCAT1 and SMILR expression is lower in the blood plasma of TAA patients. Decreased LUCAT1 expression in TAA patients' blood plasma may have diagnostic potential in discriminating patients with TAA.

Indexed as

Genetic MarkersAdultAgedAged, 80 and overAortic Aneurysm, ThoracicCase-Control StudiesFemaleGene Expression ProfilingGene Expression RegulationHumansMaleMiddle AgedRNA, Long NoncodingROC CurveGenetic Markerslong non-coding RNA LUCAT1, humanMALAT1 long non-coding RNA, humanRNA, Long Noncoding

Identifiers

PMID32655720
PMCPMC7317319
OpenAlexW3036822260

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.